Evidence map›Paper›PMID 32302253›Full record

ArticlePsychological science2020

Comparison of Adopted and Nonadopted Individuals Reveals Gene-Environment Interplay for Education in the UK Biobank.

Rosa Cheesman, Avina Hunjan, Jonathan R I Coleman, Yasmin Ahmadzadeh, Robert Plomin, Tom A McAdams, Thalia C Eley, Gerome Breen

Abstract read
In one paragraph

Article in Psychological science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Genetics and Socioeconomic Status: Some Preliminary Evidence on Mechanisms.Journal of political economy microeconomics · 2025
    Article
  5. Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
  6. Review
  7. Article
  8. The Genetics of Intelligence.Deutsches Arzteblatt international · 2025
    Review
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  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosa CheesmanSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.ORCID 0000-0002-6543-0402
Avina HunjanSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.
Jonathan R I ColemanSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.
Yasmin AhmadzadehSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.
Robert PlominSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.
Tom A McAdamsSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.
Thalia C EleySocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.
Gerome BreenSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London.

Funding

Department of HealthMedical Research Council G19/2Medical Research Council MC_PC_17228Medical Research Council MC_QA137853Medical Research Council MR/M021475/1Wellcome TrustWellcome Trust 107706/Z/15/Z
6 · The paper itself

Abstract

Polygenic scores now explain approximately 10% of the variation in educational attainment. However, they capture not only genetic propensity but also information about the family environment. This is because of passive gene-environment correlation, whereby the correlation between offspring and parent genotypes results in an association between offspring genotypes and the rearing environment. We measured passive gene-environment correlation using information on 6,311 adoptees in the UK Biobank. Adoptees' genotypes were less correlated with their rearing environments because they did not share genes with their adoptive parents. We found that polygenic scores were twice as predictive of years of education in nonadopted individuals compared with adoptees (

Indexed as

AdoptionBiological Specimen BanksEducational StatusGene-Environment InteractionAdultAgedFemaleGenotypeHumansMaleMiddle AgedMultifactorial InheritanceParentsRegression AnalysisUnited Kingdomadoptioneducational attainmentgene-environment interplaypolygenic scores

Identifiers

PMID32302253
PMCPMC7238511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.