Evidence map›Paper›PMID 32302101›Full record

ArticleBiochemistry2020

Inhibition of Excision of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Excision Repair Factor XPC-RAD23B.

Marina Kolbanovskiy, Yoonjung Shim, Jung-Hyun Min, Nicholas E Geacintov, Vladimir Shafirovich

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marina KolbanovskiyChemistry Department, New York University, 31 Washington Place, New York, New York 10003-5180, United States.
Yoonjung ShimDepartment of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, United States.
Jung-Hyun MinDepartment of Chemistry and Biochemistry, Baylor University, Waco, Texas 76798, United States.
Nicholas E GeacintovChemistry Department, New York University, 31 Washington Place, New York, New York 10003-5180, United States.
Vladimir ShafirovichChemistry Department, New York University, 31 Washington Place, New York, New York 10003-5180, United States.ORCID 0000-0001-8225-6509
New York University · USBaylor University · USUniversity of Illinois Chicago · US

Funding

Interplay between DNA repair mechanisms in human cells and extractsR01ES027059 · NIEHS · NEW YORK UNIVERSITY · PI SHAFIROVICH, VLADIMIR · 2016 to 2020
$1.8M
NIEHS NIH HHS R01 ES027059
6 · The paper itself

Abstract

The interplay between nucleotide excision repair (NER) and base excision repair (BER) of nonbulky, oxidatively generated DNA lesions has long been a subject of significant interest. The hydantoin oxidation products of 8-oxoguanine, spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh), are substrates of both BER and NER in HeLa cell extracts and human cells [Shafirovich, V., et al. (2019)

Indexed as

Binding, CompetitiveDNADNA-Binding ProteinsDNA GlycosylasesDNA RepairDNA Repair EnzymesHumansHydantoinsMolecular ConformationOxidation-ReductionDNADNA-Binding ProteinsDNA GlycosylasesDNA Repair EnzymesHydantoinsNEIL1 protein, humanRAD23B protein, humanXPC protein, human

Identifiers

PMID32302101
PMCPMC7413705
OpenAlexW3016454999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.