Evidence map›Paper›PMID 32301646›Full record

SynthesisRadiology2020

Diagnostic Performance of CT and Reverse Transcriptase Polymerase Chain Reaction for Coronavirus Disease 2019: A Meta-Analysis.

Hyungjin Kim, Hyunsook Hong, Soon Ho Yoon

Registry-linked trialAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05279378 (Correlation of Lung Ultrasonography With Chest CT Findings in Cancer Patients With COVID-19 Viral Pneumonia, an Observational Study), which is not on this map. Cited by 308 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
308citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05279378 completednot on this mapstarted 2022, after this paper: background citation

Correlation of Lung Ultrasonography With Chest CT Findings in Cancer Patients With COVID-19 Viral Pneumonia, an Observational Study

Typeobservational_patient_registrySponsorSouth Egypt Cancer InstituteRan2022 to 2025Enrolled30ConditionsCancer PatientsArmslung ultrasonography versus CT
3 · Its place in the literature

Who cites it

308 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  7. Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid and antibody tests up to 22 August 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
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  10. Chest CT abnormalities in COVID-19: a systematic review.International journal of medical sciences · 2021
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248 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hyungjin Kim *From the Department of Radiology, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea (H.K., S.H.Y.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (H.K., S.H.Y.); and Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea (H.H.).ORCID 0000-0003-0722-0033
Hyunsook Hong *From the Department of Radiology, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea (H.K., S.H.Y.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (H.K., S.H.Y.); and Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea (H.H.).ORCID 0000-0003-0955-4176
Soon Ho YoonFrom the Department of Radiology, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea (H.K., S.H.Y.); Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea (H.K., S.H.Y.); and Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea (H.H.).ORCID 0000-0002-3700-0165

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Recent studies have suggested that chest CT scans could be used as a primary screening or diagnostic tool for coronavirus disease 2019 (COVID-19) in epidemic areas. Purpose To perform a meta-analysis to evaluate diagnostic performance measures, including predictive values of chest CT and initial reverse transcriptase polymerase chain reaction (RT-PCR). Materials and Methods Medline and Embase were searched from January 1, 2020, to April 3, 2020, for studies on COVID-19 that reported the sensitivity, specificity, or both of CT scans, RT-PCR assays, or both. The pooled sensitivity and specificity were estimated by using random-effects models. The actual prevalence (ie, the proportion of confirmed patients among those tested) in eight countries was obtained from web sources, and the predictive values were calculated. Meta-regression was performed to reveal the effect of potential explanatory factors on the diagnostic performance measures. Results The pooled sensitivity was 94% (95% confidence interval [CI]: 91%, 96%;

Indexed as

Clinical Laboratory TechniquesReverse Transcriptase Polymerase Chain ReactionTomography, X-Ray ComputedBetacoronavirusChinaCoronavirus InfectionsCOVID-19COVID-19 TestingHumansPandemicsPneumonia, ViralPrevalenceSARS-CoV-2Sensitivity and Specificity

Identifiers

PMID32301646
PMCPMC7233409

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.