ArticleAngewandte Chemie (International ed. in English)2020
DNA-Polymer Nanostructures by RAFT Polymerization and Polymerization-Induced Self-Assembly.
Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 70 citations in OpenAlex.
- Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Overview on the Sensing Materials and Methods Based on Reversible Addition-Fragmentation Chain-Transfer Polymerization.Biosensors · 2025Review
- RNA-Polymer Conjugates via Direct Incorporation of the Chain Transfer Agent and PET-RAFT Polymerization.Biomacromolecules · 2025Article
- Open-Vessel and Scalable Synthesis of Linear and Branched Poly(meth)acrylic Acid via Light-Mediated Atom Transfer Radical Polymerization in Water.Macromolecules · 2025Article
- Generation of topologically defined linear and cyclic DNA bottle brush polymersPolymer chemistry · 2025Article
- Fluorescent Polymers via Coordination ofPolymers · 2024Article
- Beyond Lipids: Exploring Advances in Polymeric Gene Delivery in the Lipid Nanoparticles Era.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Aqueous photo-RAFT polymerization under ambient conditions: synthesis of protein-polymer hybrids in open air.Chemical science · 2024Article
- Surface Hybridization Chain Reaction of Binary Mixture DNA-PEG Corona Nanostructures Produced by Low-Volume RAFT-Mediated Photopolymerization-Induced Self-Assembly.Bioconjugate chemistry · 2023Article
- Biomass RNA for the Controlled Synthesis of Degradable Networks by Radical Polymerization.ACS nano · 2023Article
- A Versatile and Efficient Method to Isolate DNA-Polymer Conjugates.ACS macro letters · 2023Article
- Synthesis of RNA-Amphiphiles via Atom Transfer Radical Polymerization in the Organic Phase.Precision chemistry · 2023Article
- A Perspective on the History and Current Opportunities of Aqueous RAFT Polymerization.Macromolecular rapid communications · 2022Article
- RAFT-mediated polymerization-induced self-assembly (RAFT-PISA): current status and future directions.Chemical science · 2022Review
- Functional DNA-Polymer Conjugates.Chemical reviews · 2021Review
- Constructing helical nanowiresRSC advances · 2021Article
- Directional effect on the fusion of ellipsoidal morphologies into nanorods and nanotubes.RSC advances · 2021Article
- DNA Functional Nanomaterials for Controlled Delivery of Nucleic Acid-Based Drugs.Frontiers in bioengineering and biotechnology · 2021Review
- Proapoptotic Peptide Brush Polymer Nanoparticles via Photoinitiated Polymerization-Induced Self-Assembly.Angewandte Chemie (International ed. in English) · 2020Article
- DNA-Polymer Nanostructures by RAFT Polymerization and Polymerization-Induced Self-Assembly.Angewandte Chemie (International ed. in English) · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Nanostructures derived from amphiphilic DNA-polymer conjugates have emerged prominently due to their rich self-assembly behavior; however, their synthesis is traditionally challenging. Here, we report a novel platform technology towards DNA-polymer nanostructures of various shapes by leveraging polymerization-induced self-assembly (PISA) for polymerization from single-stranded DNA (ssDNA). A "grafting from" protocol for thermal RAFT polymerization from ssDNA under ambient conditions was developed and utilized for the synthesis of functional DNA-polymer conjugates and DNA-diblock conjugates derived from acrylates and acrylamides. Using this method, PISA was applied to manufacture isotropic and anisotropic DNA-polymer nanostructures by varying the chain length of the polymer block. The resulting nanostructures were further functionalized by hybridization with a dye-labelled complementary ssDNA, thus establishing PISA as a powerful route towards intrinsically functional DNA-polymer nanostructures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.