Evidence map›Paper›PMID 32301251›Full record

ArticleCancer medicine2020

Depression and anxiety in Hodgkin lymphoma patients: A Danish nationwide cohort study of 945 patients.

Andreas K Øvlisen, Lasse H Jakobsen, Kristian H Kragholm, René E Nielsen, Martin Hutchings, Rasmus B Dahl-Sørensen, Henrik Frederiksen, Danny Stoltenberg, Martin Bøgsted, Lene S G Østgård and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Patients' Attitude toward Less Frequent Surveillance of Low-Risk Pancreatic Cysts: A Multicenter European Cohort Study.Medical decision making : an international journal of the Society for Medical Decision Making · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Andreas K ØvlisenDepartment of Haematology, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0002-4631-9936
Lasse H JakobsenDepartment of Haematology, Aalborg University Hospital, Aalborg, Denmark.
Kristian H KragholmDepartment of Cardiology, Unit of Epidemiology and Biostatistics, Aalborg University Hospital, Aalborg, Denmark.
René E NielsenDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Martin HutchingsDepartment of Haematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Rasmus B Dahl-SørensenDepartment of Haematology, Zealand University Hospital, Roskilde, Denmark.
Henrik FrederiksenDepartment of Haematology, Odense University Hospital, Odense, Denmark.
Danny StoltenbergDepartment of Haematology, Copenhagen University Hospital, Herlev, Denmark.
Martin BøgstedDepartment of Haematology, Aalborg University Hospital, Aalborg, Denmark.
Lene S G ØstgårdDepartment of Haematology, Aarhus University Hospital, Aarhus, Denmark.
Marianne T SeverinsenDepartment of Haematology, Aalborg University Hospital, Aalborg, Denmark.
Tarec C El-GalalyDepartment of Haematology, Aalborg University Hospital, Aalborg, Denmark.
Aalborg University Hospital · DKAarhus University Hospital · DKCopenhagen University Hospital · DKHerlev Hospital · DKOdense University Hospital · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-related psychological distress may lead to depression and anxiety among survivors. The vast majority of patients with Hodgkin lymphoma (HL) become long-term survivors, but the risk of mental health problems after HL is not well-characterized. Using national population-based registries, we investigated the cumulative incidence of psychotropic drug (antidepressants, antipsychotics, and anxiolytics) use (proxies for depression and anxiety) in HL patients as well as if an increased risk would normalize over time for patients in remission. The study included 945 HL patients aged 18-92 years and 4725 matched persons. In total, 215 HL patients (22.8%) received a prescription of any psychotropic drug (PD) at some point after date of diagnosis compared to 545 persons (11.5%) in the matched cohort. Cumulative incidences with death/relapse as competing risk confirmed that HL patients were at higher risk of receiving psychotropic drug prescriptions, but the increased risk was transient and normalized to the matched population 5 years into survivorship. Increased age, Eastern Cooperative Oncology Group performance status, and disease stage were associated with higher risk of psychotropic drug prescriptions. Given the increased rate of psychotropic drug prescriptions after HL diagnosis, screening for symptoms of depression and anxiety is warranted after HL diagnosis and first years into survivorship.

Indexed as

Quality of LifeAdolescentAdultAnxietyCancer SurvivorsCohort StudiesDenmarkDepressionFemaleFollow-Up StudiesHodgkin DiseaseHumansIncidenceMaleMiddle AgedPrognosisanxietydepressionepidemiologyHodgkin lymphomapsychotropic drugs

Identifiers

PMID32301251
PMCPMC7300408
OpenAlexW3017133006

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.