Evidence map›Paper›PMID 32301033›Full record

ArticleMolecular diversity2021

One-pot sequential coupling reactions as a new practical protocol for the synthesis of unsymmetrical 2,3-diethynyl quinoxalines and 4-ethynyl-substituted pyrrolo[1,2-a]quinoxalines.

Ali Keivanloo, Saeed Lashkari, Mohammad Bakherad, Mahsa Fakharian, Sima Abbaspour

Abstract read
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In one paragraph

Article in Molecular diversity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ali KeivanlooFaculty of Chemistry, Shahrood University of Technology, Shahrood, 36199-95161, Iran. akeivanloo@yahoo.com.
Saeed LashkariFaculty of Chemistry, Shahrood University of Technology, Shahrood, 36199-95161, Iran.
Mohammad BakheradFaculty of Chemistry, Shahrood University of Technology, Shahrood, 36199-95161, Iran.
Mahsa FakharianFaculty of Chemistry, Shahrood University of Technology, Shahrood, 36199-95161, Iran.
Sima AbbaspourFaculty of Chemistry, Shahrood University of Technology, Shahrood, 36199-95161, Iran.
University of Shahrood · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One palladium-catalyzed sequential coupling reactions were successfully used as a new protocol for the synthesis of unsymmetrical 2,3-diethynyl quinoxalines and 4-ethynyl-substituted pyrrolo[1,2-a]quinoxalines. The one-pot two coupling reactions of 2,3-dichloroquinoxaline, with two different terminal alkynes, under controlled conditions produced selectively unsymmetrical 2,3-diethynyl quinoxalines with high yields. When one of the two terminal alkynes was 3-propyne-1-ol, in the presence of secondary amines, cyclization occurred and 4-ethynyl-substituted pyrrolo[1,2-a]quinoxalines were successfully formed. All synthesized compounds were tested against the two bacterial strains including Micrococcus luteus and Pseudomonas aeruginosa.

Indexed as

Anti-Bacterial AgentsPyrrolesQuinoxalinesCatalysisMicrococcus luteusPalladiumPseudomonas aeruginosaAnti-Bacterial AgentsPalladiumPyrrolesQuinoxalinesAntibacterial activityCoupling reactionsPropargyl alcoholPyrrolo[1,2-a]quinoxalineTerminal alkyne

Identifiers

PMID32301033
OpenAlexW3016675803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.