Evidence map›Paper›PMID 32300739›Full record

ArticleEClinicalMedicine2020

Long-term clinical prognosis of human infections with avian influenza A(H7N9) viruses in China after hospitalization.

Qianli Wang, Hui Jiang, Yun Xie, Tianchen Zhang, Shelan Liu, Shenggen Wu, Qianlai Sun, Shaoxia Song, Wei Wang, Xiaowei Deng and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Safety and Efficacy of Pulmonary Rehabilitation for Long COVID Patients Experiencing Long-Lasting Symptoms.International journal of environmental research and public health · 2024
    Article
  2. Review
  3. Observational
  4. Article
  5. Review
  6. Observational
  7. Post-COVID lung fibrosis: The tsunami that will follow the earthquake.Lung India : official organ of Indian Chest Society · 2021
    Review
  8. Article
  9. Avian influenza overview November 2019- February2020.EFSA journal. European Food Safety Authority · 2020
    Article
  10. Long COVID: "And the fire rages on".Lung India : official organ of Indian Chest Society
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 3 countries.

Qianli WangSchool of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China.
Hui JiangChinese Center for Disease Control and Prevention, Beijing, China.
Yun XieJiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Tianchen ZhangJiangxi Provincial Center for Disease Control and Prevention, Nanchang, China.
Shelan LiuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
Shenggen WuFujian Provincial Center for Disease Control and Prevention, Fuzhou, China.
Qianlai SunHunan Provincial Center for Disease Control and Prevention, Changsha, China.
Shaoxia SongShandong Provincial Center for Disease Control and Prevention, Jinan, China.
Wei WangSchool of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China.
Xiaowei DengSchool of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China.
Lingshuang RenSchool of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China.
Tiantian QinZhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Peter HorbyCenter for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.
Timothy UyekiInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Hongjie YuSchool of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China.
Fudan University · CNNanchang Center for Disease Control and Prevention · CNCapital Medical University · CNGansu Provincial Center for Disease Control and Prevention · CNHunan Provincial Center for Disease Control and Prevention · CNNational Center for Immunization and Respiratory Diseases · USShandong Center for Disease Control and Prevention · CNUniversity of Oxford · GBZhejiang Center for Disease Control and Prevention · CNZhengzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMainland China has experienced five epidemics of human cases of avian influenza A(H7N9) virus infection since 2013. We conducted a prospective study to assess long-term clinical, pulmonary function testing, and chest computed tomography (CT) imaging findings after patients were discharged from hospital.

methodsA(H7N9) survivors in five provinces and one municipality underwent follow-up visits from August 2013 to September 2018, at three, six, and 12 months after illness onset, and a subset was also assessed at 18 and 64 months after onset. Thirteen patients were enrolled from the first A(H7N9) epidemic in 2013, 36 from the 2013-2014 second epidemic, and 12 from the 2016-2017 fifth epidemic. At each visit, A(H7N9) survivors received a medical examination, including the mMRC (modified Medical Research Council) dyspnea scale assessment, chest auscultation, pulmonary function testing and chest CT scans.

findingsThe median age of 61 A(H7N9) survivors was 50 years. The cumulative rate of pulmonary dysfunction was 38·5% and 78·2% for chest CT scan abnormalities at the end of follow-up. Restrictive ventilation dysfunction was common during follow-up. Mild dyspnea was documented at three to 12-month follow-up visits.

interpretationPatients who survived severe illness from A(H7N9) virus infection had evidence of persistent lung damage and long-term pulmonary dysfunction.

fundingNational Science Fund for Distinguished Young Scholars (grant number 81525023); Program of Shanghai Academic/Technology Research Leader (grant number 18XD1400300); National Science and Technology Major Project of China (grant numbers 2017ZX10103009-005, 2018ZX10201001-010).

Indexed as

CT, computed tomographyCT scanDLCO, diffusion capacity of carbon monoxideFEV1, forced expiratory volume in 1 secondFollow-upFVC, forced vital capacityGGO, ground-glass opacityH7N9 subtypeICU, intensive care unitIQR, interquartile rangemMRC, modified Medical Research CouncilPrognosisRespiratory function testsRT-PCR, reverse transcriptase polymerase chain reactionSD, standard deviationSPSS, Statistical Package for Social SciencesWHO, World Health Organization

Identifiers

PMID32300739
PMCPMC7152818
OpenAlexW3008062805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.