Evidence map›Paper›PMID 32300705›Full record

ReviewJournal of frailty, sarcopenia and falls2018

Adverse events and safety issues associated with physical activity and exercise for adults with osteoporosis and osteopenia: A systematic review of observational studies and an updated review of interventional studies.

Setor K Kunutsor, Sarah Leyland, Dawn A Skelton, Laura James, Matthew Cox, Nicola Gibbons, Julie Whitney, Emma M Clark

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of frailty, sarcopenia and falls, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Guideline
  4. Pooled it
  5. Effects of a resistance and balance exercise programme on physical fitness, health-related quality of life and fear of falling in older women with osteoporosis and vertebral fracture: a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Trial
  6. Article
  7. Review
  8. The impact of yoga on aging physiology: A review.The journal of nutrition, health & aging · 2024
    Review
  9. Review
  10. Review
  11. Exercise programmes for ankylosing spondylitis.The Cochrane database of systematic reviews · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Setor K KunutsorNational Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, UK.
Sarah LeylandNational Osteoporosis Society, Camerton, Bath, UK.
Dawn A SkeltonSchool of Health & Life Sciences, Centre for Living, Glasgow Caledonian University, Glasgow.
Laura JamesDepartment of Academic Physiotherapy, King's College London, London, UK.
Matthew CoxDepartment of Academic Physiotherapy, King's College London, London, UK.
Nicola GibbonsDepartment of Academic Physiotherapy, King's College London, London, UK.
Julie WhitneyDepartment of Academic Physiotherapy, King's College London, London, UK.
Emma M ClarkMusculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Southmead Hospital, Bristol, UK.
King's College London · GBHealth & Life (Taiwan) · TWRoyal Osteoporosis Society · GBSouthmead Hospital · GBUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe conducted a systematic review to identify adverse effects of physical activity and/or exercise for adults with osteoporosis/osteopenia. We synthesised evidence from observational studies, and updated three previously published systematic reviews.

methodsWe searched MEDLINE, EMBASE, CINAHL, Web of Science, grey literature and reference lists of relevant studies. Selection criteria were: (1) observational studies in patients with osteoporosis/osteopenia; and (2) in accordance with the criteria used in the previous reviews. A narrative synthesis was conducted for the observational data. Random effects meta-analysis was undertaken for the review updates.

resultsFor the observational synthesis 14 studies were included. The majority of studies reported no adverse events, reduced incidence/improvement, or no significant change after physical activity or exercise. Activities that involved spinal flexion (certain yoga moves and sit-ups) were associated with a greater risk of vertebral fractures but these events were rare. For the update of reviews, 57 additional studies were identified. Exercise was generally associated with a greater number of minor adverse events including mild muscle/joint pain. Serious adverse events were rare and could not be attributed to the intervention.

conclusionPatients with osteoporosis/osteopenia can safely participate in structured exercise programmes, whether at home or in supervised facilities.

Indexed as

Adverse eventsExerciseOsteoporosisPhysical activitySystematic review

Identifiers

PMID32300705
PMCPMC7155356
OpenAlexW2902207537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.