Evidence map›Paper›PMID 32300432›Full record

ArticleJournal of hematology2018

Vasculitis in Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia: A Report of Two Cases.

Justin Jacobse, Yvo W J Sijpkens, Jan W van 't Wout, Elke E M Peters, L Tom Vlasveld

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Ischemic stroke as the initial presentation in acute myeloid leukemia vs. myelodysplastic syndrome: a case report and literature review with pathophysiological and clinical exploration.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justin JacobseDepartment of Internal Medicine, HMC Bronovo, The Hague, Netherlands.
Yvo W J SijpkensDepartment of Internal Medicine, HMC Bronovo, The Hague, Netherlands.
Jan W van 't WoutDepartment of Internal Medicine, HMC Bronovo, The Hague, Netherlands.
Elke E M PetersDepartment of Pathology, HMC Bronovo, The Hague, Netherlands.
L Tom VlasveldDepartment of Internal Medicine, HMC Bronovo, The Hague, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a clear association between myelodysplastic syndrome (MDS)/chronic myelomonocytic leukemia (CMML) and autoimmune manifestations such as vasculitis. It is not clear if autoimmune manifestations in myelodysplastic syndrome are a cause or consequence. We describe two patients with polyarteritis nodosa and large vessel vasculitis, as presenting symptom of a myelodysplastic syndrome with excess blasts type 2 and chronic myelomonocytic leukemia respectively. Immunosuppressive treatment resulted in amelioration of the vasculitis with improvement of the myelodysplastic features in the first patient and rapid evolution to acute myeloid leukemia in the other patient. The association between MDS/CMML and autoimmune manifestations, such as vasculitis, emphasizes the role of autoimmunity in the clinical features and even pathogenesis of MDS/CMML.

Indexed as

Autoimmune manifestationChronic myelomonocytic leukemiaImmunosuppressionMyelodysplastic syndrome with excess blastsVasculitis

Identifiers

PMID32300432
PMCPMC7155851

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Registered trials

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