Evidence map›Paper›PMID 32300398›Full record

ArticleJournal of hematology2017

Regulatory and Memory B Lymphocytes in Children With Newly Diagnosed Immune Thrombocytopenia.

Asmaa M Zahran, Sanaa Shaker Aly, Ahmed Elabd, Ismail Lotfy Mohamad, Khalid I Elsayh

Open access · greenAbstract read
In one paragraph

Article in Journal of hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Asmaa M ZahranClinical Pathology Department, South Egypt Cancer Institute, Assiut, Egypt.
Sanaa Shaker AlyClinical and Chemical Pathology Department, Faculty of Medicine, South Valley University, Qena, Egypt.
Ahmed ElabdPediatric Department, Faculty of Medicine, South Valley University, Qena, Egypt.
Ismail Lotfy MohamadPediatric Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Khalid I ElsayhPediatric Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Assiut University · EGSouth Valley University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmune (idiopathic) thrombocytopenic purpura (ITP) is a primary autoimmune disease. It is characterized by a diminished peripheral platelet count (< 100 × 10

methodsThis study was a case-control study. The study included 30 patients with acute ITP. The patients were recruited from Pediatric Clinical Hematology Unit of Children Hospital, Assiut University. In addition, 20 healthy children of comparable age and sex were taken as controls. The institutional review board approved the study and informed consents were obtained.

resultsThere is a significant alteration of B-cell homeostasis in patients with ITP.

conclusionAnalysis of Bregs and memory B cells could serve as prognostic markers and might guide therapy in ITP patients in the future.

Indexed as

B lymphocytesChildrenImmuneThrombocytopenia

Identifiers

PMID32300398
PMCPMC7155846
OpenAlexW2755653578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.