Evidence map›Paper›PMID 32300348›Full record

ArticleFrontiers in immunology2020

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors.

Claudia Alicata, Elham Ashouri, Neda Nemat-Gorgani, Lisbeth A Guethlein, Wesley M Marin, Sudan Tao, Lorenzo Moretta, Jill A Hollenbach, John Trowsdale, James A Traherne and 3 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  13. High-Resolution Characterization ofFrontiers in immunology · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Claudia AlicataDepartment of Immunology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Elham AshouriDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Neda Nemat-GorganiDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Lisbeth A GuethleinDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Wesley M MarinDepartment of Neurology, University of California, San Francisco, San Francisco, CA, United States.
Sudan TaoBlood Center of Zhejiang Province, Hangzhou, China.
Lorenzo MorettaDepartment of Immunology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Jill A HollenbachDepartment of Neurology, University of California, San Francisco, San Francisco, CA, United States.
John TrowsdaleDivision of Immunology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.
James A TraherneDivision of Immunology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.
Abbas GhaderiSchool of Medicine, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
Peter ParhamDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.
Paul J NormanDepartment of Structural Biology, Stanford University School of Medicine, Stanford, CA, United States.

Funding

Insights Into Immune-Related Diseases Born from Population GenomicsU01AI090905 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Paul John Norman · 2010 to 2026
$10.9M
STRUCTURAL BIOLOGY OF HLA-A,B ANTIGENSR01AI017892 · NIAID · STANFORD UNIVERSITY · PI PARHAM, PETER R · 1985 to 2019
$6.1M
Integrated Exchange and Storage of Current- and Future-Generation Immunogenomic DataR01AI128775 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JILL Allison HOLLENBACH, STEVEN JOHN MACK · 2017 to 2026
$4.5M
NIAID NIH HHS R01 AI017892NIAID NIH HHS R01 AI128775NIAID NIH HHS U01 AI090905
6 · The paper itself

Abstract

Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands. Directly impacting NK cell function,

Indexed as

AllelesArabsHaplotypesHistocompatibility Antigens Class IHumansIranKiller Cells, NaturalPolymorphism, GeneticReceptors, KIRHistocompatibility Antigens Class IReceptors, KIRHLA class Iimmune diversityIranian populationsKIRNK cells

Identifiers

PMID32300348
PMCPMC7142237

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.