ArticleFrontiers in psychiatry2020
Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Alexithymia and Inflammatory Bowel Disease: A Systematic Review.Frontiers in psychology · 2020Pooled it
- Effects of a Footbathing Intervention on Physiological, Endocrine, and Psychological Status in Japanese University Students: A Randomized Controlled Trial.International journal of environmental research and public health · 2024Trial
- Somatic and gastrointestinal symptoms longitudinally predict early adolescent disordered eating.Journal of pediatric gastroenterology and nutrition · 2026Article
- The WISH 2.0 Intervention for Irritable Bowel Syndrome: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2026Article
- Listening to the Body: Interoceptive Awareness and Eating Disorder Vulnerability in Adolescents with Inflammatory Bowel Diseases.Children (Basel, Switzerland) · 2026Article
- The Gut-Brain Axis-From Science to Clinical Practice.Gastro hep advances · 2026Review
- Multimodal Psychophysiological Assessment Reveals Gastric but Not Cardiac Interoception Deficits in Disorders of Gut-Brain Interaction.Psychophysiology · 2025Article
- Interpreting Anxiety Disorders From the Perspective of Interoceptive Computational Models.Brain and behavior · 2025Review
- Observing the Influence of Shame and Guilt in Inflammatory Bowel Disease: A Systematic Review.Clinical neuropsychiatry · 2025Review
- Impaired gastric and urinary but preserved cardiac interoception in women with endometriosis.PloS one · 2025Article
- Psychological determinants of irritable bowel syndrome and its impact on quality of life: a machine learning approaches.Gastroenterology and hepatology from bed to bench · 2025Article
- Emotional Disturbances and Crohn's Disease.Clinical practice and epidemiology in mental health : CP & EMH · 2025Review
- Interoceptive Processing in Functional Gastrointestinal Disorders.International journal of molecular sciences · 2024Review
- Unmet needs of drugs for irritable bowel syndrome and inflammatory bowel diseases: interest of vagus nerve stimulation and hypnosis.Inflammopharmacology · 2024Review
- Relationship Between Psychological Trauma and Irritable Bowel Syndrome and Functional Dyspepsia in a Joint Hypermobility Syndrome/Ehlers-Danlos Syndrome Patient Population.Digestive diseases and sciences · 2024Article
- Anorexia and bulimia in relation to ulcerative colitis: a Mendelian randomization study.Frontiers in nutrition · 2024Article
- Relationship Between Sensitivity to Disgust and Irritable Bowel Syndrome: A Study on Healthy Individuals.Clinical neuropsychiatry · 2022Article
- Adult patients with allied disorders of Hirschsprung's disease in emergency department: An 11-year retrospective study.World journal of gastrointestinal surgery · 2022Article
- Anatomical Evidence for the Neural Connection from the Emotional Brain to Autonomic Innervation in the Anterior Chamber Structures of the Eye.Current medical science · 2022Article
- Role of mesenteric component in Crohn's disease: A friend or foe?World journal of gastrointestinal surgery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alexithymia is usually described by three main dimensions difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). The most commonly used questionnaire investigating alexithymia, the Toronto Alexithymia Scale (TAS-20), supports this three-factor structure. One important assumption is that alexithymia severity is associated to vulnerability to somatic diseases, among them gastrointestinal disorders. However, the association between alexithymia and gastrointestinal disorders is not systematic, thus questioning the role of alexithymia as a vulnerability factor for those illnesses. A recent factor analysis suggested another four-factor structure for the TAS-20: difficulties in awareness of feelings (DAF), difficulties in interoceptive abilities (DIA), externally oriented thinking (EOT), and poor affective sharing (PAS). We assume that DIA and DAF might be more relevant to investigate the association between alexithymia and gastrointestinal disorders. The rationale is that DIA and DAF reflect impairments in emotion regulation that could contribute to an inappropriate autonomic and HPA axis homeostasis in irritable bowel syndrome (IBS), ulcerative colitis (UC), or Crohn's disease (CD). The aim of this study was to investigate whether DIA and DAF are associated with the presence of IBS, UC or CD, while checking for anxiety, depression, parasympathetic (vagus nerve) activity and cortisol levels. We recruited control participants (n=26), and patients in remission who were diagnosed with IBS (n=24), UC (n=18), or CD (n=21). Participants completed questionnaires to assess anxiety, depression, and alexithymia. A blood sample and an electrocardiogram were used to measure the level of cortisol and parasympathetic activity, respectively. Logistic regressions with the four-factor structure of the TAS-20 revealed that DIA was a significant predictor of IBS (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.