ArticleFrontiers in psychiatry2020
Dynamic Functional Connectivity Patterns in Schizophrenia and the Relationship With Hallucinations.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 53 citations in OpenAlex.
- Decreased variability of small-world propensity during non-response tasks in schizophrenia.Neuroimage. Reports · 2026Article
- Classifying schizophrenia patients and healthy individuals: Whole brain SPECT functional connectivity using support vector machine classification.Neuroimage. Reports · 2026Article
- Dynamic Co-Modulation (DyCoM): A Unified Operator Framework for Dynamic Connectivity in Neuroimaging.bioRxiv : the preprint server for biology · 2026Article
- Decreased Broca-left supplementary motor area connectivity underlying auditory verbal hallucination: A resting-state NIRS study.Translational psychiatry · 2026Article
- Understanding Schizophrenia Pathophysiology via fMRI-Based Information Theory and Multiplex Network Analysis.Entropy (Basel, Switzerland) · 2026Article
- A novel framework to quantify dynamic convergence and divergence of overlapping brain states characterizing four psychiatric disorders.Network neuroscience (Cambridge, Mass.) · 2026Article
- Mental time travel and insight in schizophrenia.Psychological medicine · 2025Review
- From neuronal to mental topography - Neurophenomenology of auditory hallucinations.Translational psychiatry · 2025Review
- Studying time-resolved functional connectivity via communication theory: on the complementary nature of phase synchronization and sliding window Pearson correlation.bioRxiv : the preprint server for biology · 2025Article
- Lateralized brain connectivity in auditory verbal hallucinations: fMRI insights into the superior and middle temporal gyri.Frontiers in human neuroscience · 2025Article
- A working model of neural activity and phenomenal experience in psychosis.Molecular psychiatry · 2024Review
- Real-time fMRI neurofeedback modulates induced hallucinations and underlying brain mechanisms.Communications biology · 2024Article
- Functional magnetic resonance imaging in schizophrenia: current evidence, methodological advances, limitations and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- fMRI fluctuations within the language network are correlated with severity of hallucinatory symptoms in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2023Article
- Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia.Communications biology · 2023Article
- Altered static and dynamic functional connectivity of habenula in first-episode, drug-naïve schizophrenia patients, and their association with symptoms including hallucination and anxiety.Frontiers in psychiatry · 2023Article
- Article
- Neuroimaging biomarkers for detecting schizophrenia: A resting-state functional MRI-based radiomics analysis.Heliyon · 2022Article
- Abnormal interhemispheric and intrahemispheric functional connectivity dynamics in drug-naïve first-episode schizophrenia patients with auditory verbal hallucinations.Human brain mapping · 2022Article
- Changes in dynamic transitions between integrated and segregated states underlie visual hallucinations in Parkinson's disease.Communications biology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a wealth of evidence showing aberrant functional connectivity (FC) in schizophrenia but with considerable variability in findings across studies. Dynamic FC is an extension of traditional static FC, in that such analyses allow for explorations of temporal changes in connectivity. Thereby they also provide more detailed information on connectivity abnormalities in psychiatric disorders such as schizophrenia. The current study investigated dynamic FC in a sample of 80 schizophrenia patients and 80 matched healthy control subjects, replicating previous findings of aberrant dwell times in specific FC states, and further supporting a role for default mode network (DMN) dysfunction. Furthermore, relationships with hallucinations, a core symptom of schizophrenia, were explored. Two measures of hallucinations were used, one measure of current hallucination severity assessed on the day of scanning, and one trait-measure where hallucinations were assessed repeatedly over the course of 1 year. Current hallucination severity did not show a significant relationship with dynamic FC. However, the trait-measure of hallucination proneness over 1 year showed a significant relationship with dynamic FC. Patients with high hallucination proneness spent less time in connectivity states characterized by strong anti-correlation between the DMN and task-positive networks. The findings support theoretical models of hallucinations which have proposed an instability of the DMN and impaired cognitive control in patients with hallucinations. Furthermore, the results point to hallucination proneness as a potential marker for identifying distinct subgroups of schizophrenia patients.
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