Evidence map›Paper›PMID 32300270›Full record

ArticleJournal of orthopaedics

Development and validation of machine learning algorithms for postoperative opioid prescriptions after TKA.

Akhil Katakam, Aditya V Karhade, Joseph H Schwab, Antonia F Chen, Hany S Bedair

Abstract read
In one paragraph

Article in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Moving towards the use of artificial intelligence in pain management.European journal of pain (London, England) · 2025
    Pooled it
  2. Pooled it
  3. Machine learning in knee arthroplasty: specific data are key-a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Pooled it
  4. Joint-specific measures improve risk adjustment in total knee arthroplasty: A machine learning approach.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
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  17. Using machine learning to classify patients on opioid use.Journal of pharmaceutical health services research : an official journal of the Royal Pharmaceutical Society of Great Britain · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akhil KatakamDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Aditya V KarhadeDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Joseph H SchwabDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Antonia F ChenDepartment of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Hany S BedairDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aims of this study were to develop machine learning algorithms for preoperative prediction of prolonged opioid prescriptions after TKA and to identify variables that can predict the probability of this adverse outcome.

methodsFive algorithms were developed for prediction of prolonged postoperative opioid prescriptions.

resultsThe stochastic gradient boosting (SGB) model had the best performance. Age, history of preoperative opioid use, marital status, diagnosis of diabetes, and several preoperative medications were predictive of prolonged postoperative opioid prescriptions.

conclusionThe SGB algorithm developed could help improve preoperative identification of TKA patients at risk for prolonged postoperative opioid prescriptions.

Indexed as

Machine learningOpioidPrediction

Identifiers

PMID32300270
PMCPMC7152687

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.