Evidence map›Paper›PMID 32300201›Full record

ArticleScientific reports2020

Full genome sequencing of archived wild type and vaccine rinderpest virus isolates prior to their destruction.

Simon King, Paulina Rajko-Nenow, Honorata M Ropiak, Paolo Ribeca, Carrie Batten, Michael D Baron

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Proteomic Applications in Vaccine Development.Advances in experimental medicine and biology · 2026
    Review
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  3. Article
  4. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simon KingThe Pirbright Institute, Ash Road, Pirbright, Surrey, GU24 0NF, UK.
Paulina Rajko-NenowThe Pirbright Institute, Ash Road, Pirbright, Surrey, GU24 0NF, UK.
Honorata M RopiakThe Pirbright Institute, Ash Road, Pirbright, Surrey, GU24 0NF, UK.
Paolo RibecaThe Pirbright Institute, Ash Road, Pirbright, Surrey, GU24 0NF, UK.
Carrie BattenThe Pirbright Institute, Ash Road, Pirbright, Surrey, GU24 0NF, UK.
Michael D BaronThe Pirbright Institute, Ash Road, Pirbright, Surrey, GU24 0NF, UK. michael.baron@pirbright.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007037
6 · The paper itself

Abstract

When rinderpest virus (RPV) was declared eradicated in 2011, the only remaining samples of this once much-feared livestock virus were those held in various laboratories. In order to allow the destruction of our institute's stocks of RPV while maintaining the ability to recover the various viruses if ever required, we have determined the full genome sequence of all our distinct samples of RPV, including 51 wild type viruses and examples of three different types of vaccine strain. Examination of the sequences of these virus isolates has shown that the African isolates form a single disparate clade, rather than two separate clades, which is more in accord with the known history of the virus in Africa. We have also identified two groups of goat-passaged viruses which have acquired an extra 6 bases in the long untranslated region between the M and F protein coding sequences, and shown that, for more than half the genomes sequenced, translation of the F protein requires translational frameshift or non-standard translation initiation. Curiously, the clade containing the lapinised vaccine viruses that were developed originally in Korea appears to be more similar to the known African viruses than to any other Asian viruses.

Indexed as

Whole Genome SequencingBase SequenceDNA, ComplementaryGene LibraryGenome, ViralPhylogenyRinderpest virusRNA, ViralViral VaccinesVirionDNA, ComplementaryRNA, ViralViral Vaccines

Identifiers

PMID32300201
PMCPMC7162898

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.