ArticleScientific reports2020
Peripapillary microvascular changes in patients with systemic hypertension: An optical coherence tomography angiography study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Application of Optical Coherence Tomography Angiography in Systemic Hypertension: A Meta-Analysis.Frontiers in medicine · 2021Pooled it
- The Inter-Eye Differences of the Circumpapillary Microvasculature in Primary Open-Angle Glaucoma.Translational vision science & technology · 2026Article
- Evaluating the effect of systemic hypertension on retinal, optic nerve head microvasculature and field of vision using optical coherence tomography angiography and visual field analyzer.BMC ophthalmology · 2025Observational
- Effect of Circadian Blood Pressure Variations on Retinal Microvascular Structures: Optical Coherence Tomography Angiography Analysis with the Nighttime Divided into Subintervals (Retinal Dawn Pattern).Medicina (Kaunas, Lithuania) · 2025Article
- Barriers in Healthcare to the Use of Optical Coherence Tomography Angiography in Multiple Sclerosis.Neurology and therapy · 2025Review
- Retinal vascular alterations as assessment indicators of atherosclerotic cardiovascular disease risk in dyslipidemia patients.Frontiers in cardiovascular medicine · 2025Article
- Peripapillary Microvascular and Structural Parameters in Atrophic Nonarteritic Anterior Ischemic Optic Neuropathy, Unaffected Fellow Eyes and Controls in an Indian Population.Neuro-ophthalmology (Aeolus Press) · 2025Article
- Using deep learning to screen OCTA images for hypertension to reduce the risk of serious complications.Frontiers in cell and developmental biology · 2025Article
- Study of the impact of the vascular systemic risk factors on peripapillary vascular density by optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Observational
- Axial length, more than aging, decreases the thickness and superficial vessel density of retinal nerve fiber layer in non-glaucomatous eyes.International ophthalmology · 2024Article
- The Eye as the Window to the Heart: Optical Coherence Tomography Angiography Biomarkers as Indicators of Cardiovascular Disease.Journal of clinical medicine · 2024Review
- Changes in peripapillary microvasculature in patients with type 2 diabetes patients: effect of systemic hypertension.Scientific reports · 2023Article
- Comparison of Retinal Structural and Neurovascular Changes between Patients with and without Amyloid Pathology.Journal of clinical medicine · 2023Article
- Optical Coherence Tomography Angiography (OCTA) Differences in Vessel Perfusion Density and Flux Index of the Optic Nerve and Peri-Papillary Area in Healthy, Glaucoma Suspect and Glaucomatous Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Different characteristics of retinal damage between chronic hypertension and hypertensive retinopathy.Scientific reports · 2022Article
- Association of Neuroretinal Thinning and Microvascular Changes with Hypertension in an Older Population in Southern Italy.Journal of clinical medicine · 2022Article
- Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature.Circulation · 2022Article
- Corneal endothelial cell density and microvascular changes of retina and optic disc in autosomal dominant polycystic kidney disease.Indian journal of ophthalmology · 2021Article
- Quantitative assessment and determinants of the papillary microvasculature in healthy subjects.BMC ophthalmology · 2021Article
- Choriocapillaris microvasculature dysfunction in systemic hypertension.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to investigate changes in peripapillary microvasculature using optical coherence tomography angiography (OCTA) in systemic hypertension (HTN) patients. This was a cross-sectional study. Based on the duration of HTN, seventy-eight HTN patients were divided into two groups. (HTN group 1: <10 years, 38 eyes; HTN group 2: ≥10 years, 40 eyes) and 90 control subjects. All subjects underwent 6 × 6 mm OCTA scan centered on the optic nerve head. We analyzed peripapillary vessel density (VD) and perfusion density (PD) in superficial capillary plexus among three groups. The average ganglion cell-inner plexiform layer (GC-IPL) and retinal nerve fiber layer (RNFL) thicknesses of HTN group 2 were thinner than those of the control group (p = 0.016, and 0.035, respectively). HTN group 2 showed lower peripapillary VD and PD than the control group. However, there were no differences between HTN group 1 and the control group in OCT and peripapillary OCTA parameters. In HTN patients, the peripapillary VD, PD and GC-IPL, RNFL thicknesses correlated significantly. OCTA showed that the peripapillary VD and PD were lower in HTN patients with a duration ≥10 years compared with those of normal controls. Peripapillary microvasculature was correlated with the RNFL and GC-IPL thicknesses. HTN duration should therefore be considered when evaluating peripapillary microvasculature using OCTA.
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