Evidence map›Paper›PMID 32299796›Full record

ArticleAnnals of the rheumatic diseases2021

Antirheumatic agents in covid-19: is IL-6 the right target?

Pier Leopoldo Capecchi, Pietro Enea Lazzerini, Luca Volterrani, Maria Antonietta Mazzei, Barbara Rossetti, Giacomo Zanelli, David Bennett, Elena Bargagli, Federico Franchi, Matteo Cameli and 3 more

Open access · bronzeAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Annals of the rheumatic diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Pier Leopoldo CapecchiDepartment of Medical Sciences, Surgery and Neurosciences, Section of Internal Medicine, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy capecchipl@unisi.it.ORCID 0000-0001-7021-7764
Pietro Enea LazzeriniDepartment of Medical Sciences, Surgery and Neurosciences, Section of Internal Medicine, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Luca VolterraniDepartment of Medical Sciences, Surgery and Neurosciences, Section of Radiology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Maria Antonietta MazzeiDepartment of Medical Sciences, Surgery and Neurosciences, Section of Radiology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Barbara RossettiSection of Infectious Diseases, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Giacomo ZanelliDepartment of Medical Biotechnologies, Section of Infectious Diseases, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
David BennettSection of Pneumology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Elena BargagliDepartment of Medical Sciences, Surgery and Neurosciences, Section of Pneumology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Federico FranchiDepartment of Medical Sciences, Surgery and Neurosciences, Section of Intensive Care, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Matteo CameliDepartment of Medical Biotechnologies, Section of Cardiology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Serafina ValenteSection of Cardiology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Luca CantariniDepartment of Medical Sciences, Surgery and Neurosciences, Section of Rheumatology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
Bruno FredianiDepartment of Medical Sciences, Surgery and Neurosciences, Section of Rheumatology, COVID-19 Unit, Siena University Hospital, Siena, Toscana, Italy.
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidCOVID-19HumansInterleukin-6SARS-CoV-2Antirheumatic AgentsInterleukin-6antirheumatic agentscardiovascular diseasesinflammationpatient care team

Identifiers

PMID32299796
OpenAlexW3016792971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.