Evidence map›Paper›PMID 32299514›Full record

ArticleVeterinary research2020

Capsulized faecal microbiota transplantation ameliorates post-weaning diarrhoea by modulating the gut microbiota in piglets.

Wenjie Tang, Daiwen Chen, Bing Yu, Jun He, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Yuheng Luo, Junqiu Luo, Quyuan Wang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 49 citations in OpenAlex.

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  15. Gut Health and Influencing Factors in Pigs.Animals : an open access journal from MDPI · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Wenjie TangAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Daiwen ChenAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China. dwchen@sicau.edu.cn.
Bing YuAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Jun HeAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Zhiqing HuangAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Ping ZhengAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Xiangbing MaoAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Yuheng LuoAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Junqiu LuoAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Quyuan WangAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Huifen WangAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China.
Jie YuAnimal Nutrition Institute, Sichuan Agricultural University and Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education of China, Chengdu, China. yujie@sicau.edu.cn.
Sichuan Agricultural University · CN

Funding

China Agriculture Research System CARS-35National Natural Science Foundation of China 31672436National Natural Science Foundation of China 31730091
6 · The paper itself

Abstract

Early weaning-induced stress causes diarrhoea, thereby reducing the growth performance of piglets. Gut bacterial dysbiosis has emerged as a leading cause of post-weaning diarrhoea. The present study aimed to investigate the effect of capsulized faecal microbiota transplantation (FMT) on the gut bacterial community, immune response and gut barrier function of piglets. Thirty-two weaned barrows were randomly divided into two groups. The recipient group was inoculated orally with capsulized faecal microbiota of healthy Tibetan pigs during the whole period of the trial, while the control group was given an empty capsule. The feed-to-gain ratio, diarrhoea ratio, and histological damage score of recipient piglets were significantly decreased. FMT treatment significantly increased the colon length of piglets. Furthermore, the relative abundances of Firmicutes, Euryarchaeota, Tenericutes, Lactobacillus, and Methanobrevibacter in the colon of recipient piglets were increased, and the relative abundances of Campylobacter and Proteobacteria were significantly decreased compared with those in the control group. CD4

Indexed as

Gastrointestinal MicrobiomeImmunity, InnateAnimalsDiarrheaFecal Microbiota TransplantationMaleSus scrofaSwineSwine DiseasesWeaning

Identifiers

PMID32299514
PMCPMC7164362
OpenAlexW3016335885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.