Evidence map›Paper›PMID 32299387›Full record

ArticleBMC neurology2020

Lenticulostriate arteries appearance before thrombectomy predicts good outcome in acute middle cerebral artery occlusion.

Feifeng Liu, Chen Chen, Lan Hong, Hao Shen, Wenjie Cao, Qiang Dong, Xinyi Yang, Mengruo Guo, Ying Li, Yaping Xiao and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Feifeng LiuDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Chen ChenDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Lan HongDepartment of Neurology, Shanghai huashan hospital, Fudan University, Shanghai, China.
Hao ShenDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Wenjie CaoDepartment of Neurology, Shanghai huashan hospital, Fudan University, Shanghai, China.
Qiang DongDepartment of Neurology, Shanghai huashan hospital, Fudan University, Shanghai, China.
Xinyi YangDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Mengruo GuoDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Ying LiDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Yaping XiaoDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China.
Xin ChengDepartment of Neurology, Shanghai huashan hospital, Fudan University, Shanghai, China.
Gang LiDepartment of Neurology, Shanghai East Hospital, Tongji University, Shanghai, China. ligang@tongji.edu.cn.

Funding

Chinese Cardiovascular Association-V.G found (2017-CCA-VG-025Shanghai Science and Technology Commission Grant No. 16511105000-16511105002the Key Disciplines Group Construction Project of Pudong Health Bureau of Shanghai Grant No. PWZxq2017-08the Outstanding Leaders Training Program of Pudong New Area Health System of Shanghai Grant No. PWRl2018-01
6 · The paper itself

Abstract

backgroundEndovascular therapy is widely used in acute large vessel occlusion. This study investigated whether imaging of lateral lenticulostriate arteries (LSAs) before thrombectomy would potentially be helpful for predicting prognosis of patients with acute M1 segment of middle cerebral artery occlusion (MCAO).

methods59 consecutive patients with acute M1 segment of MCAO treated with mechanical thrombectomy at two comprehensive stroke centers were analyzed. Patients were categorized into LSA+ (appearing of lateral LSAs) and LSA- (sparing of lateral LSAs) group according to preprocedural digital substraction angiography (DSA). Baseline data and clinical outcomes were compared. A good clinical outcome was defined as a modified Rankin Scale score of 0 to 2 at 3 months. The association between clinical and imaging parameters and functional outcome was evaluated with logistic regression analysis.

resultsLSA+ was shown in 36 patients (61%). LSA+ group had a significantly higher proportion of good outcome (72.2% vs. 8.7%, OR 27.3,95% CI 5.38-138.4, P < 0.001), lower risk of symptomatic intracranial haemorrhages (sICH) (8.3% vs. 47.8%,OR 0.10,95% CI 0.02-0.42, P = 0.001) and lower mortality in hospital (5.6% vs. 34.8%, OR 0.11,95% CI 0.02-0.58, P < 0.004) compared with LSA- group. Patients in LSA+ group had lower baseline NIHSS score(P < 0.01) and NIHSS score at 14 days(P < 0.01) and smaller infarct core volume (P = 0.016) on computed tomography perfusion imaging (CTP) compared to the LSA- group. Multivariate logistic regression analysis showed that a small infarct core volume (OR 6.74,95% CI 1.148-39.569, P = 0.035) and LSA+(OR 22.114,95% CI 3.339-146.470, P = 0.001) were associated with a good clinical outcome.

conclusionsOur data suggest that appearance of lateral LSAs before mechanical thrombectomy would be potentially helpful for predicting favorable prognosis of patients with acute M1 segment of MCAO.

Indexed as

AgedAged, 80 and overFemaleHumansInfarction, Middle Cerebral ArteryIntracranial HemorrhagesMaleMiddle AgedMiddle Cerebral ArteryRetrospective StudiesThrombectomyTomography, X-Ray ComputedTreatment OutcomeIschemic strokeLenticulostriate arteryMiddle cerebral artery occlusionOutcomeThrombectomy

Identifiers

PMID32299387
PMCPMC7161229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.