ArticleBMC infectious diseases2020
Emergence of carbapenem-resistant and colistin-susceptible Enterobacter cloacae complex co-harboring bla
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 56 citations in OpenAlex.
- Comparative Genomics of theViruses · 2026Article
- Adaptive colistin resistance dynamics inMicrobiology spectrum · 2026Article
- Emergence of concurrently transmissibleMicrobiology spectrum · 2025Article
- Polymyxin resistance in Enterobacter cloacae complex in Brazil: phenotypic and molecular characterization.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Genome sequences ofMicrobiology resource announcements · 2024Article
- Bacteria carrying mobile colistin resistance genes and their control measures, an updated review.Archives of microbiology · 2024Review
- VIM-1-producing Enterobacter asburiae with mobile colistin resistance genes from wastewaters.BMC genomics · 2024Article
- The emergence of clonally diverse carbapenem-resistant Enterobacter cloacae complex in West Bengal, India: a dockyard of β-lactamases periling nosocomial infections.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Integrated Analysis of Patient Networks and Plasmid Genomes to Investigate a Regional, Multispecies Outbreak of Carbapenemase-Producing Enterobacterales Carrying Both blaIMP and mcr-9 Genes.The Journal of infectious diseases · 2024Article
- Molecular eidemiology of carbapenem-resistant Enterobacter cloacae complex in a tertiary hospital in Shandong, China.BMC microbiology · 2023Article
- Assessment of Prevalence and Diversity of Antimicrobial ResistantAntibiotics (Basel, Switzerland) · 2023Article
- First report of coexistence ofFrontiers in microbiology · 2023Article
- Molecular epidemiology and genomic characterization of a plasmid-mediatedComputational and structural biotechnology journal · 2023Article
- Genomic and clinical characteristics of carbapenem-resistantFrontiers in microbiology · 2023Article
- Modified Drug-Susceptibility Testing and Screening Culture Agar for Colistin-SusceptibleJournal of clinical microbiology · 2022Article
- Plasmidome in mcr-1 harboring carbapenem-resistant enterobacterales isolates from human in Thailand.Scientific reports · 2022Article
- Molecular characteristics of global β-lactamase-producing Enterobacter cloacae by genomic analysis.BMC microbiology · 2022Article
- Chromosomal coharboring of blaBMC infectious diseases · 2022Article
- Antimicrobial Resistance and Biofilms Underlying Catheter-Related Bloodstream Coinfection byAntibiotics (Basel, Switzerland) · 2022Article
- Colistin Resistance Mechanism inPathogens (Basel, Switzerland) · 2022Article
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9 authors at 2 institutions in 1 country.
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Abstract
backgroundThe spread of Enterobacteriaceae producing both carbapenemases and Mcr, encoded by plasmid-mediated colistin resistance genes, has become a serious public health problem worldwide. This study describes three clinical isolates of Enterobacter cloacae complex co-harboring bla
methodsThirty-two clinical isolates of E. cloacae complex non-susceptible to carbapenems were obtained from patients at 14 hospitals in Japan. Their minimum inhibitory concentrations (MICs) were determined by broth microdilution methods and E-tests. Their entire genomes were sequenced by MiSeq and MinION methods. Multilocus sequence types were determined and a phylogenetic tree constructed by single nucleotide polymorphism (SNP) alignment of whole genome sequencing data.
resultsAll 32 isolates showed MICs of ≥2 μg/ml for imipenem and/or meropenem. Whole-genome analysis revealed that all these isolates harbored bla
conclusionThe mcr-9 is silently distributed among carbapenem-resistant E. cloacae complex isolates, of which are emerging in hospitals in Japan. To our knowledge, this is the first report of isolates of E. cloacae complex harboring both bla
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