ArticleBMC infectious diseases2020
A descriptive epidemiological study of the incidence of newly diagnosed Lyme disease cases in a UK primary care cohort, 1998-2016.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence of Lyme Borreliosis in Europe: A Systematic Review (2005-2020).Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2023Pooled it
- Resident primary care practitioners' awareness and handling of zoonotic diseases: an explorative online survey in the Hameln-Pyrmont district, Lower Saxony, Germany.BMC primary care · 2025Article
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- Incidence and management of Lyme disease: a Scottish general practice retrospective study.BJGP open · 2024Article
- Real-world evidence from the first online healthcare analytics platform-Livingstone. Validation of its descriptive epidemiology module.PLOS digital health · 2023Article
- Mapping and monitoring tick (Acari, Ixodida) distribution, seasonality, and host associations in the United Kingdom between 2017 and 2020.Medical and veterinary entomology · 2023Article
- Seroepidemiology ofMicroorganisms · 2022Article
- Regional seropositivity for Borrelia burgdorferi and associated risk factors: findings from the Rhineland Study, Germany.Parasites & vectors · 2022Article
- One Health Approach to Tick and Tick-Borne Disease Surveillance in the United Kingdom.International journal of environmental research and public health · 2022Review
- Seroprevalence of antibodies against Borrelia burgdorferi sensu lato in healthy blood donors in Romania: an update.Parasites & vectors · 2021Article
- Article
- Potential for online crowdsourced biological recording data to complement surveillance for arthropod vectors.PloS one · 2021Article
- Zoonotic Tick-Borne Pathogens in Temperate and Cold Regions of Europe-A Review on the Prevalence in Domestic Animals.Frontiers in veterinary science · 2020Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundPrimary care is likely to see the highest number of Lyme disease patients. Despite this, there is limited published data regarding Lyme disease patients accessing primary care in the UK. We aim to describe trends in the incidence of a new diagnosis, and demographics of patients identified in a primary care electronic health database.
methodsA descriptive epidemiological study of Lyme disease coded patients in UK primary care. 3725 patients coded for Lyme disease during 1998-2016 were identified within The Health Improvement Network (THIN). Incidence rates and the demographics of cases identified were described. Poisson regression was used to analyse socio-demographic characteristics of the cases.
resultsThere was an increase in annual crude incidence rates, peaking in 2015 at 5.47 (95% CI 4.85-6.14) cases per 100,000 population per year. Multivariable analysis showed there were significant differences in the ages of those affected, incidence of a new diagnosis rose as deprivation levels improved, and that there was a higher incidence of cases living in rural areas compared to urban areas. There was no significant difference between sexes for the UK. Cases were significantly more likely to identify with being white compared to the national population.
conclusionsAn increasing incidence of patients newly coded with Lyme disease related Read codes was identified using data from a UK national primary care database. By comparing these incidence figures with national laboratory-confirmed surveillance data, a multiplication factor of 2.35 (95%CI 1.81-2.88) can be calculated in order to estimate the annual number of cases seen in primary care. The significant socio-demographic variables associated with a Lyme disease diagnosis likely reflect a complex interplay of socio-economic issues, which needs to be further explored. Future work is needed to examine the treatment and management of patients within this database.
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