ArticleBMC evolutionary biology2020
Host-parasite interactions in non-native invasive species are dependent on the levels of standing genetic variation at the immune locus.
Article in BMC evolutionary biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 20 citations in OpenAlex.
- Avian malaria and invasion success: Contrasting infection patterns in two introduced Eurasian sparrows in North America (International journal for parasitology. Parasites and wildlife · 2026Article
- Baylisascaris procyonis on the rise in Europe: a comprehensive review and analysis of occurrence data.Parasitology research · 2025Review
- New tools to uncover old tricks: an update on the knowledge on the most successful invasive freshwater helminth, Schyzocotyle acheilognathi.Parasitology research · 2025Review
- Comparative genomic analysis of immune-related genes and chemosensory receptors provides insights into the evolution and adaptation of four major domesticated Asian carps.BMC genomics · 2025Article
- Predictive multi-omic biomarkers for urban zoonotic spillover detection: an integrative review.Frontiers in public health · 2025Review
- Harnessing genomic technologies for one health solutions in the tropics.Globalization and health · 2024Review
- Evidence of predation pressure on sensitive species by raccoons based on parasitological studies.International journal for parasitology. Parasites and wildlife · 2024Article
- Population genetic structure of Indoplanorbis exustus (Gastropoda: Planorbidae) in Thailand and its infection with trematode cercariae.PloS one · 2024Article
- Non-MHC immunity genes do not affect parasite load in European invasive populations of common raccoon.Scientific reports · 2023Article
- Helminths in Invasive Raccoons (Pathogens (Basel, Switzerland) · 2023Article
- Complex patterns shape immune genes diversity during invasion of common raccoon in Europe - Selection in action despite genetic drift.Evolutionary applications · 2023Article
- A molecular survey of spotted fever group rickettsiae in introduced raccoons (Procyon lotor).Parasites & vectors · 2022Article
- Copro-Molecular Identification of Tapeworms in Introduced Invasive Carnivores in Poland.Pathogens (Basel, Switzerland) · 2022Article
- Digestive tract nematode infections in non-native invasive American mink with the first molecular identification ofInternational journal for parasitology. Parasites and wildlife · 2021Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundParasites may mediate the success of biological invasions through their effect on host fitness and thus, on host population growth and stability. However, a release from the pressure of parasites is strongly related to the genetic differentiation of the host. In invasive host populations, the number of available genetic variants, allowing them to 'fight' the infection, are likely to be influenced by founder events and genetic drift. The level standing genetic variation of invasive populations may be crucial in successfully adapting to new environments and resisting diseases. We studied invasive populations of raccoon that experienced a random reduction in genetic diversity during the establishment and evaluated the relationship between host immune genetic diversity and intestinal parasites infection.
resultsWe distinguished two different genetic clusters that are characterized by different sets of functionally relevant MHC-DRB alleles. Both clusters were characterized by considerably different allele-parasite associations and different levels of parasite infection. The specific resistance MHC-DRB alleles explained the lower prevalence of Digenea parasites. An increased infection intensity was related to the presence of two MHC-DRB alleles. One of these alleles significantly decreased in frequency over time, causing a decrease of Digenea abundance in raccoons in consecutive years.
conclusionsOur findings suggest that intestinal parasites can exert selective pressure on an invasive host with lowered levels of immune genetic diversity and contribute to promoting local adaptation over time. The random genetic drift that created the two different genetic clusters in the invasive raccoon range imposed completely different MHC-parasite associations, strongly associated with the infection status of populations. Our findings underline the role of standing genetic variation in shaping host-parasite relationships and provide empirical support that functional genetic variation may be, at least partly, responsible for differences in the success of invasive populations.
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