ArticleStroke2020
Low-Frequency Oscillations Are a Biomarker of Injury and Recovery After Stroke.
Article in Stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06147167 (Effects of Individualized iTBS on Upper Limb Function After Stroke), which is not on this map. Cited by 81 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Individualized iTBS on Upper Limb Function After Stroke
Who cites it
81 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- EEG biomarkers for assessment, prognosis, and monitoring of natural upper limb recovery after stroke: a systematic review.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Biomarkers of stroke recovery using EEG-based resting-state functional connectivity: a systematic review.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Dissociable effects of β-tACS on spectral power and network organization for proximal versus distal upper-limb recovery in subacute stroke: double-blind, randomized, sham-controlled trial with high-density EEG.Journal of neuroengineering and rehabilitation · 2026Trial
- Weakened Effective Connectivity Related to Electroacupuncture in Stroke Patients with Prolonged Flaccid Paralysis: An EEG Pilot Study.Neural plasticity · 2021Trial
- Post-stroke rehabilitative mechanisms in individualized fatigue level-controlled treadmill training in rats.Neural regeneration research · 2026Article
- Slow Oscillations Track Acute Stroke Injury but Not Functional Recovery.bioRxiv : the preprint server for biology · 2026Article
- Large-scale neural slowing measured with electroencephalography indexes secondary thalamic degeneration in stroke.medRxiv : the preprint server for health sciences · 2026Article
- NeuroStat: An Open-Source EEG Connectivity Platform for Randomised Controlled Trials.Sensors (Basel, Switzerland) · 2026Article
- Adaptive Neural Reorganization Enables Real-Time Finger-Level Robotic Control in BCI-Naïve Stroke Survivors.bioRxiv : the preprint server for biology · 2026Article
- Resting-state neural oscillations of the motor system influence the resting motor threshold.Scientific reports · 2026Observational
- White Matter Infarct Detection with Transformer and Auto-ML-Derived Models.Brain sciences · 2026Article
- Cortical Oscillations as an Endophenotype Mediating ApoE-ε2 Effects on Poststroke Functional Status.Stroke · 2026Article
- Lesion-specific EEG signatures in stroke: a multi-scale framework integrating oscillations, connectivity, and asymmetry for machine learning decoding.Journal of neuroengineering and rehabilitation · 2026Article
- Enhancing upper limb motor recovery prediction after acute stroke using EEG and subacute data.APL bioengineering · 2026Article
- Stroke and motor outcomes are associated with regional and age-specific changes in periodic and aperiodic cortical activity.Experimental physiology · 2026Article
- Uncovering oscillatory dysregulation associated with suicide risk in major depressive disorder: a narrative review.Translational psychiatry · 2026Review
- Stroke recovery beyond initial severity: the complementary roles of brain structure and brain function in acute stroke.Brain communications · 2026Article
- Prefrontal Hierarchical Control of Corticomuscular Coherence in Stroke.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Electroencephalography in stroke Care: From acute monitoring to Post-Stroke epilepsy.Clinical neurophysiology practice · 2026Review
- Functional connectivity associated with severe upper limb impairment in resting-state electroencephalography among chronic stroke survivors: a machine learning approach.Journal of neuroengineering and rehabilitation · 2025Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Background and Purpose- Low-frequency oscillations reflect brain injury but also contribute to normal behaviors. We examined hypotheses relating electroencephalography measures, including low-frequency oscillations, to injury and motor recovery poststroke. Methods- Patients with stroke completed structural neuroimaging, a resting-state electroencephalography recording and clinical testing. A subset admitted to an inpatient rehabilitation facility also underwent serial electroencephalography recordings. The relationship that electroencephalography measures (power and coherence with leads overlying ipsilesional primary motor cortex [iM1]) had with injury and motor status was assessed, focusing on delta (1-3 Hz) and high-beta (20-30 Hz) bands. Results- Across all patients (n=62), larger infarct volume was related to higher delta band power in bilateral hemispheres and to higher delta band coherence between iM1 and bilateral regions. In chronic stroke, higher delta power bilaterally correlated with better motor status. In subacute stroke, higher delta coherence between iM1 and bilateral areas correlated with poorer motor status. These coherence findings were confirmed in serial recordings from 18 patients in an inpatient rehabilitation facility. Here, interhemispheric coherence between leads overlying iM1 and contralesional M1 was elevated at inpatient rehabilitation facility admission compared with healthy controls (n=22), declining to control levels over time. Decreases in interhemispheric coherence between iM1 and contralesional M1 correlated with better motor recovery. Conclusions- Delta band coherence with iM1 related to greater injury and poorer motor status subacutely, while delta band power related to greater injury and better motor status chronically. Low-frequency oscillations reflect both injury and recovery after stroke and may be useful biomarkers in stroke recovery and rehabilitation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.