Evidence map›Paper›PMID 32299165›Full record

ArticleAnimal bioscience2021

Genetic evaluation of sheep for resistance to gastrointestinal nematodes and body size including genomic information.

Tatiana Saraiva Torres, Luciano Silva Sena, Gleyson Vieira Dos Santos, Luiz Antonio Silva Figueiredo Filho, Bruna Lima Barbosa, Antônio de Sousa Júnior, Fábio Barros Britto, José Lindenberg Rocha Sarmento

Open access · goldAbstract read
In one paragraph

Article in Animal bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tatiana Saraiva TorresDepartment of Animal Science, Federal University of Piauí, Teresina, PI 64049-550, Brazil.
Luciano Silva SenaDepartment of Animal Science, Federal University of Piauí, Teresina, PI 64049-550, Brazil.
Gleyson Vieira Dos SantosDepartment of Animal Science, Federal University of Piauí, Bom Jesus, PI 64900-000, Brazil.
Luiz Antonio Silva Figueiredo FilhoFederal Institute of Education, Science and Technology of Maranhão, Caxias, MA 65609-899, Brazil.
Bruna Lima BarbosaDepartment of Animal Science, Federal University of Piauí, Teresina, PI 64049-550, Brazil.
Antônio de Sousa JúniorTechnical College of Teresina, Federal University of Piauí, Teresina, PI 64049-550, Brazil.
Fábio Barros BrittoDepartment of Biology, Federal University of Piauí, Teresina, PI 64049-550, Brazil.
José Lindenberg Rocha SarmentoDepartment of Animal Science, Federal University of Piauí, Teresina, PI 64049-550, Brazil.
Universidade Federal do Piauí · BRInstituto Federal do Maranhão · BR

Funding

Brazilian National Institute of Science and Technology in Animal ScienceCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorFederal University of PiauíFoundation for Support to Research and Scientific and Technological Development of MaranhãoNational Council for Scientific and Technological Development
6 · The paper itself

Abstract

objectiveThe genetic evaluation of Santa Inês sheep was performed for resistance to gastrointestinal nematode infection (RGNI) and body size using different relationship matrices to assess the efficiency of including genomic information in the analyses.

methodsThere were 1,637 animals in the pedigree and 500, 980, and 980 records of RGNI, thoracic depth (TD), and rump height (RH), respectively. The genomic data consisted of 42,748 SNPs and 388 samples genotyped with the OvineSNP50 BeadChip. The (co)variance components were estimated in single- and multi-trait analyses using the numerator relationship matrix (A) and the hybrid matrix H, which blends A with the genomic relationship matrix (G). The BLUP and single-step genomic BLUP methods were used. The accuracies of estimated breeding values and Spearman rank correlation were also used to assess the feasibility of incorporating genomic information in the analyses.

resultsThe heritability estimates ranged from 0.11±0.07, for TD (in single-trait analysis using the A matrix), to 0.38±0.08, for RH (using the H matrix in multi-trait analysis). The estimates of genetic correlation ranged from -0.65±0.31 to 0.59±0.19, using A, and from -0.42±0.30 to 0.57±0.16 using H. The gains in accuracy of estimated breeding values ranged from 2.22% to 75.00% with the inclusion of genomic information in the analyses.

conclusionThe inclusion of genomic information will benefit the direct selection for the traits in this study, especially RGNI and TD. More information is necessary to improve the understanding on the genetic relationship between resistance to nematode infection and body size in Santa Inês sheep. The genetic evaluation for the evaluated traits was more efficient when genomic information was included in the analyses.

Indexed as

AccuracyGenetic ParametersRump HeightssGBLUPWorm Infection

Identifiers

PMID32299165
PMCPMC7961268
OpenAlexW3016229547

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.