Evidence map›Paper›PMID 32298827›Full record

Observational studyWorld neurosurgery2020

Challenges, Learning Curve, and Safety of Endoscopic Endonasal Surgery of Sellar-Suprasellar Lesions in a Community Hospital.

Mohamed A R Soliman, Sydney Eaton, Elise Quint, Abdullah F Alkhamees, Saba Shahab, Avalon O'Connor, Erika Haberfellner, Jacob Im, Abdurrahim A Elashaal, Francis Ling and 4 more

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Chordoma: Genetics and Contemporary Management.International journal of molecular sciences · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 3 countries.

Mohamed A R SolimanNeurosurgery Department, Cairo University, Cairo, Egypt; Schulich School of Medicine and Density, Western University, London. Electronic address: moh.ar.sol@kasralainy.edu.eg.
Sydney EatonSchulich School of Medicine and Density, Western University, London.
Elise QuintSchulich School of Medicine and Density, Western University, London.
Abdullah F AlkhameesSchulich School of Medicine and Density, Western University, London; Neurosurgery Department, Qassim University, Qassim, Kingdom of Saudi Arabia.
Saba ShahabSchulich School of Medicine and Density, Western University, London.
Avalon O'ConnorSchulich School of Medicine and Density, Western University, London.
Erika HaberfellnerSchulich School of Medicine and Density, Western University, London.
Jacob ImSchulich School of Medicine and Density, Western University, London.
Abdurrahim A ElashaalNeurosurgery Department, Windsor Regional Hospital, Western University, ON, Canada.
Francis LingEar, Nose and Throat Department, Windsor Regional Hospital, Western University, ON, Canada.
Mustafa ElbrekiEar, Nose and Throat Department, Windsor Regional Hospital, Western University, ON, Canada.
Tommy DangNeurosurgery Department, Windsor Regional Hospital, Western University, ON, Canada.
Dante J MorassuttiNeurosurgery Department, Windsor Regional Hospital, Western University, ON, Canada.
Abdalla ShamisaNeurosurgery Department, Windsor Regional Hospital, Western University, ON, Canada.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveEndoscopic endonasal surgery (EES) for the management of sellar, suprasellar, and anterior skull base lesions is gaining popularity. Our aim was to analyze and present the clinical outcomes of EES for the management of these lesions in a community hospital setting.

methodsWe retrospectively reviewed the charts of 56 patients with sellar, suprasellar, and anterior skull base lesions who underwent EES between 2010 and 2018.

resultsThere was male predominance (53.6%) with a mean age of 54.9 ± 13.7 years. Lesions were 45 pituitary adenomas, 5 meningiomas, 3 metastatic, 1 craniopharyngioma, 1 Rathke cyst, and 1 mucocele. Gross total excision was achieved in 57.1%, subtotal excision occurred in 37.5%, and decompression and biopsy were achieved in 5.4% patients. Postoperative vision normalized or improved in 27 patients (86.1%) and was stable in 4 patients (13.9%). Recovery of a preexisting hormonal deficit occurred in 13 (23.2%) patients, and a new hormonal deficit occurred in 9 patients (16.1%). The mean hospital stay was 6.1 ± 4.9 days. Postoperative complications included cerebrospinal fluid leak in 8 patients (14.3%). Four patients (7.1%) had meningitis. Diabetes insipidus was present in 19 patients (33.9%), and postoperative intracranial hematoma requiring evacuation was necessary in 2 patients (3.6%). The mean follow-up duration was 47.5 ± 25.8 months. Lesion progression or recurrence requiring redo surgery occurred in 5 patients (8.9%). Regarding the learning curve, the postoperative cerebrospinal fluid leak, meningitis, new hormonal deficits, and diabetes insipidus decreased in the second half of the patients.

conclusionsEES provides an effective and safe surgical option with low morbidity and mortality for the treatment of sellar, suprasellar, and anterior skull base lesions in a community hospital setting.

Indexed as

EndoscopyNeurosurgical ProceduresAdultAgedAged, 80 and overCranial Fossa, AnteriorFemaleHospitals, CommunityHumansMaleMiddle AgedRetrospective StudiesSella TurcicaSkull Base NeoplasmsTreatment OutcomeClinical outcomesCommunity hospitalEndoscopic endonasal surgeryOlfactory grooveSellarSuprasellarTuberculum sellae

Identifiers

PMID32298827
PMCPMC7195030
OpenAlexW3017072796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.