Evidence map›Paper›PMID 32298769›Full record

ReviewJournal of hepatology2020

The COVID-19 pandemic will have a long-lasting impact on the quality of cirrhosis care.

Elliot B Tapper, Sumeet K Asrani

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05045924 (A Pilot Study of Remote Home Monitoring in Patients With Advanced Cirrhosis, During COVID-19, Using Wearable Technology and an App Based Interface, to Diagnose Early and Severe Cirrhosis Decompensation, and Inform Design of a Future Randomized Controlled Intervention Study.), which is not on this map. Cited by 110 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05045924 unknown statusnot on this mapstarted 2021, after this paper: background citation

A Pilot Study of Remote Home Monitoring in Patients With Advanced Cirrhosis, During COVID-19, Using Wearable Technology and an App Based Interface, to Diagnose Early and Severe Cirrhosis Decompensation, and Inform Design of a Future Randomized Controlled Intervention Study.

TypeobservationalSponsorRoyal Free Hospital NHS Foundation TrustRan2021 to 2021Enrolled40ConditionsDecompensated Cirrhosis
3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Measuring hospital care resilience: a systematic literature review.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Observational
  10. Review
  11. Telemedicine in the tertiary liver unit: A feasibility study.Clinical and experimental hepatology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Global epidemiology of cirrhosis - aetiology, trends and predictions.Nature reviews. Gastroenterology & hepatology · 2023
    Review

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Elliot B TapperDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan; Gastroenterology Section, VA Ann Arbor Healthcare System, Ann Arbor, Michigan. Electronic address: etapper@umich.edu.
Sumeet K AsraniBaylor University Medical Center, Dallas, Texas.

Funding

Optimizing Measures for Clinical Trials in Covert Hepatic EncephalopathyK23DK117055 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TAPPER, ELLIOT · 2019 to 2022
$776k
NIDDK NIH HHS K23 DK117055
6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has shattered the meticulously developed processes by which we delivered quality care for patients with cirrhosis. Care has been transformed by the crisis, but enduring lessons have been learned. In this article, we review how COVID-19 will impact cirrhosis care. We describe how this impact unfolds over 3 waves; i) an intense period with prioritized high-acuity care with delayed elective procedures and routine care during physical distancing, ii) a challenging 'return to normal' following the end of physical distancing, with increased emergent decompensations, morbidity, and systems of care overwhelmed by the backlog of deferred care, and iii) a protracted period of suboptimal outcomes characterized by missed diagnoses, progressive disease and loss to follow-up. We outline the concrete steps required to preserve the quality of care provided to patients with cirrhosis. This includes an intensification of the preventative care provided to patients with compensated cirrhosis, proactive chronic disease management, robust telehealth programs, and a reorganization of care delivery to provide a full service of care with flexible clinical staffing. Managing the pandemic of a serious chronic disease in the midst of a global infectious pandemic is challenging. It is incumbent upon the entire healthcare establishment to be strong enough to weather the storm. Change is needed.

Indexed as

BetacoronavirusCarcinoma, HepatocellularClinical Decision-MakingCoronavirus InfectionsCOVID-19Delivery of Health CareHumansLiver CirrhosisLiver NeoplasmsPandemicsPatient Care TeamPneumonia, ViralQuality of Health CareSARS-CoV-2TelemedicineHepatic encephalopathyHepatocellular carcinomaLiver diseaseTelemedicineVarices

Identifiers

PMID32298769
PMCPMC7194911

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.