Evidence map›Paper›PMID 32298639›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Tuberculosis associated with diabetes mellitus by age group in Brazil: a retrospective cohort study, 2007-2014.

Maria do Socorro Nantua Evangelista, Rosalia Maia, João Paulo Toledo, Ricardo Gadelha de Abreu, Draurio Barreira

Open access · goldAbstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. The cause-effect relation of tuberculosis on incidence of diabetes mellitus.Frontiers in cellular and infection microbiology · 2023
    Review
  4. Review
  5. Challenges of diabetes in elderly TB patients.The Indian journal of tuberculosis · 2022
    Review
  6. Observational
  7. A Saudi Arabian Public Health Perspective of Tuberculosis.International journal of environmental research and public health · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Maria do Socorro Nantua EvangelistaMinistério da Saúde, Programa Nacional de Controle da Tuberculose, Brasília, DF, Brasil; Universidade de Brasília (UnB), Brasília, DF, Brasil. Electronic address: socorrok@unb.br.
Rosalia MaiaMinistério da Saúde, Programa Nacional de Controle da Tuberculose, Brasília, DF, Brasil.
João Paulo ToledoMinistério da Saúde, Programa Nacional de Controle da Tuberculose, Brasília, DF, Brasil.
Ricardo Gadelha de AbreuMinistério da Saúde, Programa Nacional de Controle da Tuberculose, Brasília, DF, Brasil; UNITAID - WHO, Genova, Switzerland.
Draurio BarreiraUNITAID - WHO, Genova, Switzerland.
Ministério da Saúde · STUnitaid · CHUniversidade de Brasília · BR

Funding

World Health Organization 001
6 · The paper itself

Abstract

Diabetes mellitus (DM) has important implications for tuberculosis (TB), as it increases the risk for disease activation and is associated with unfavorable TB treatment outcomes. This study analyzed the association between TB and DM (TBDM) in Brazil from 2007 to 2014. This was a retrospective cohort study carried out in 709,429 new cases of TB reported to the national disease notification system of the Brazilian Ministry of Health. Sociodemographic and clinical data, test results, and treatment outcomes were analyzed. TBDM was found in 6.0% of TB cases, mostly in men aged 18-59 years. The lethality rate was 5.1% higher in all age groups with diabetes, except in those older than 60 years of age. The frequency of multi-drug-resistant tuberculosis (MDR-TB) in patients with DM was higher in those without DM, with a 1.6- to 3.8-fold increase in the odds of MDR-TB. The elderly showed an increase in the prevalence of TBDM from 14.3% to 18.2%. Women were more likely to have DM, and elderly women had 41.0% greater chance of having DM. Relapse was significant among patients younger than 17 years of age. TBDM was high in Brazil, affected all age groups, and was associated with unfavorable TB treatment outcomes. We emphasize the need for strategies for the clinical management of diabetic tuberculosis patients in Brazil aiming at minimizing relapses, deaths, and MDR-TB.

Indexed as

Age DistributionAdolescentAdultBrazilChildDiabetes MellitusDisease NotificationFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsSocioeconomic FactorsTuberculosisDiabetes mellitusMortalityTuberculosis

Identifiers

PMID32298639
PMCPMC9392016
OpenAlexW3016314845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.