Evidence map›Paper›PMID 32298284›Full record

ArticlePloS one2020

ChemOS: An orchestration software to democratize autonomous discovery.

Loïc M Roch, Florian Häse, Christoph Kreisbeck, Teresa Tamayo-Mendoza, Lars P E Yunker, Jason E Hein, Alán Aspuru-Guzik

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 139 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Autonomous Small-Angle Scattering for Accelerated Soft Material Formulation Optimization.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Accelerated chemical science with AI.Digital discovery · 2024
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Machine learning for a sustainable energy future.Nature reviews. Materials · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Loïc M RochDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.ORCID 0000-0003-1771-2023
Florian HäseDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Christoph KreisbeckDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Teresa Tamayo-MendozaDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Lars P E YunkerDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8899-2926
Jason E HeinDepartment of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.
Alán Aspuru-GuzikDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.
Harvard University · USUniversity of British Columbia · CACanadian Institute for Advanced Research · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current Edisonian approach to discovery requires up to two decades of fundamental and applied research for materials technologies to reach the market. Such a slow and capital-intensive turnaround calls for disruptive strategies to expedite innovation. Self-driving laboratories have the potential to provide the means to revolutionize experimentation by empowering automation with artificial intelligence to enable autonomous discovery. However, the lack of adequate software solutions significantly impedes the development of self-driving laboratories. In this paper, we make progress towards addressing this challenge, and we propose and develop an implementation of ChemOS; a portable, modular and versatile software package which supplies the structured layers necessary for the deployment and operation of self-driving laboratories. ChemOS facilitates the integration of automated equipment, and it enables remote control of automated laboratories. ChemOS can operate at various degrees of autonomy; from fully unsupervised experimentation to actively including inputs and feedbacks from researchers into the experimentation loop. The flexibility of ChemOS provides a broad range of functionality as demonstrated on five applications, which were executed on different automated equipment, highlighting various aspects of the software package.

Indexed as

Artificial IntelligenceComputational ChemistrySoftwareAlgorithmsAutomationChromatography, High Pressure LiquidInternet of ThingsRobotics

Identifiers

PMID32298284
PMCPMC7161969
OpenAlexW3016862866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.