ArticleACS chemical biology2020
Dual-Activatable Cell Tracker for Controlled and Prolonged Single-Cell Labeling.
Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress.FEBS open bio · 2026Article
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- A live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems.Cell discovery · 2023Article
- 9-Cyano-10-telluriumpyronin Derivatives as Red-light-activatable Raman Probes.Chemistry, an Asian journal · 2023Article
- Whispering-gallery microlasers for cell tagging and barcoding: the prospects for in vivo biosensing.Light, science & applications · 2021Article
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Authors and funding
6 authors.
Funding
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Abstract
Cell trackers are fluorescent chemical tools that facilitate imaging and tracking cells within live organisms. Despite their versatility, these dyes lack specificity, tend to leak outside of the cell, and stain neighboring cells. Here, we report a dual-activatable cell tracker for increased spatial and temporal staining control, especially for single-cell tracking. This probe overcomes the typical problems of current cell trackers: off-target staining, high background signal, and leakage from the intracellular medium. Staining with this dye is not cytotoxic, and it can be used in sensitive primary cells. Moreover, this dye is resistant to harsh fixation and permeabilization conditions and allows for multiwavelength studies with confocal microscopy and fluorescence-activated cell sorting. Using this cell tracker, we performed
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