Evidence map›Paper›PMID 32297987›Full record

ArticleJournal of medical virology2020

Off-label use of tocilizumab in patients with SARS-CoV-2 infection.

Simona Di Giambenedetto, Arturo Ciccullo, Alberto Borghetti, Giovanni Gambassi, Francesco Landi, Elena Visconti, Lorenzo Zileri Dal Verme, Roberto Bernabei, Enrica Tamburrini, Roberto Cauda and 1 more

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 4 syntheses or guidelines pooled it, 126 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Trial
  6. Trial
  7. Investigating the Short-Term Changes of the Electrocardiogram Indicators During Hospitalization in Patients With COVID-19 Following the Use of Tocilizumab.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
  8. Nomogram-based prediction model for tocilizumab-induced leukopenia in adults using FAERS and PMDA data.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Observational
  9. Article
  10. Article
  11. Review
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  14. Article
  15. Review
  16. Immunomodulatory therapies for COVID-19.Frontiers in medicine · 2022
    Review
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  18. Observational
  19. Review
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Simona Di GiambenedettoUOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Arturo CicculloUOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Alberto BorghettiUOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.ORCID 0000-0002-7910-021X
Giovanni GambassiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Francesco LandiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Elena ViscontiUOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Lorenzo Zileri Dal VermeDipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Roberto BernabeiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Enrica TamburriniUOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Roberto CaudaUOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Antonio GasbarriniDipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19SARS-CoV-2Antibodies, Monoclonal, HumanizedHumansOff-Label UsePandemicsAntibodies, Monoclonal, Humanizedtocilizumab

Identifiers

PMID32297987
PMCPMC7262080
OpenAlexW3016759737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.