Evidence map›Paper›PMID 32297843›Full record

ArticleNucleic acid therapeutics2020

Oligonucleotides and the COVID-19 Pandemic: A Perspective.

John J Rossi, Daniel Rossi

Open access · hybridAbstract read
In one paragraph

Article in Nucleic acid therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Nucleic acid drugs: recent progress and future perspectives.Signal transduction and targeted therapy · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Novel coronavirus disease (COVID-19) pandemic: A recent mini review.Computational and structural biotechnology journal · 2021
    Review
  10. Exploring the magic bullets to identify Achilles' heel in SARS-CoV-2: Delving deeper into the sea of possible therapeutic options in Covid-19 disease: An update.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021
    Review
  11. Review
  12. Review
  13. Understanding COVID-19: From Origin to Potential Therapeutics.International journal of environmental research and public health · 2020
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

John J RossiDepartment of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Daniel RossiiSTAT Therapeutics, Monrovia, California, USA.
California Library Association · USCity of Hope · US

Funding

COMBINATORIAL USE OF CCR5 RIBOZYMES WITH ANTI HIV1 RNASR01AI042552 · NIAID · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI ROSSI, JOHN JOSEPH · 1998 to 2019
$7.8M
NIAID NIH HHS R01 AI042552
6 · The paper itself

Abstract

The present global health emergency involving the emergence and rapid spread of a novel coronavirus has prompted the world scientific community to consider how it can help to fight this growing viral pandemic. With few safe and effective drugs available to combat this threat to humanity and the normal functioning of our society, the oligonucleotide research community is uniquely positioned to apply its technology and expertise to help alleviate the crisis, thanks to its capacity for rational drug design, swift development cycles, and pursuing targets undruggable by conventional treatment strategies.

Indexed as

Antiviral AgentsBetacoronavirusCoronavirus InfectionsCOVID-19Drug Delivery SystemsHumansOligonucleotidesPandemicsPneumonia, ViralSARS-CoV-2Antiviral AgentsOligonucleotideschemistry optimizationcoronavirusvirus–host interactions

Identifiers

PMID32297843
PMCPMC7249453
OpenAlexW3016726513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.