Evidence map›Paper›PMID 32297829›Full record

ArticleSLAS discovery : advancing life sciences R & D2020

A Perspective on Expanding Our Understanding of Cancer Treatments by Integrating Approaches from the Biological and Physical Sciences.

Emma J Fong, Carly Strelez, Shannon M Mumenthaler

Abstract read
In one paragraph

Article in SLAS discovery : advancing life sciences R & D, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. The Yin-Yang Dynamics in Cancer Pharmacogenomics and Personalized Medicine.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emma J FongLawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-6806-1959
Carly StrelezLawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA, USA.
Shannon M MumenthalerLawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, CA, USA.

Funding

TRANS-NETWORK PROJECTSU54CA143907 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HILLIS, WILLIAM DANIEL · 2009 to 2013
$15.2M
Multiscale systems biology modeling to exploit tumor-stromal metabolic crosstalk in colorectal cancerU01CA232137 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINLEY, STACEY DELERIA, MACKLIN, PAUL T · 2018 to 2022
$2.8M
(PQB6)An Integrative Computational and Bioengineered Tissue Model of MetastasisR01CA180149 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AGUS, DAVID B, ATALA, ANTHONY · 2013 to 2016
$2.3M
NCI NIH HHS R01 CA180149NCI NIH HHS U01 CA232137NCI NIH HHS U54 CA143907
6 · The paper itself

Abstract

Multicellular systems such as cancer suffer from immense complexity. It is imperative to capture the heterogeneity of these systems across scales to achieve a deeper understanding of the underlying biology and develop effective treatment strategies. In this perspective article, we will discuss how recent technologies and approaches from the biological and physical sciences have transformed traditional ways of measuring, interpreting, and treating cancer. During the SLAS 2019 Annual Meeting, SBI

Indexed as

Systems BiologyBiological Science DisciplinesHumansModels, TheoreticalNatural Science DisciplinesNeoplasmscancercell viabilityimagingmathematical modelingorganoidsorgan-on-chip

Identifiers

PMID32297829
PMCPMC7372587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.