Evidence map›Paper›PMID 32297730›Full record

ArticleAnalytical chemistry2020

Microfluidic Platform for the Isolation of Cancer-Cell Subpopulations Based on Single-Cell Glycolysis.

Claudia Zielke, Ching W Pan, Adriana J Gutierrez Ramirez, Cameron Feit, Chandler Dobson, Catherine Davidson, Brody Sandel, Paul Abbyad

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Claudia ZielkeDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.
Ching W PanDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.
Adriana J Gutierrez RamirezDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.
Cameron FeitDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.
Chandler DobsonDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.
Catherine DavidsonDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.ORCID 0000-0002-2523-4319
Brody SandelDepartment of Biology, Santa Clara University, Santa Clara, California 95053, United States.
Paul AbbyadDepartment of Chemistry and Biochemistry, Santa Clara University, Santa Clara, California 95053, United States.ORCID 0000-0002-8641-8533
Santa Clara University · US

Funding

Development of Platform for Passive Cell Selection Based on MetabolismR15GM129674 · NIGMS · SANTA CLARA UNIVERSITY · PI ABBYAD, PAUL · 2018 to 2018
$374k
NIGMS NIH HHS R15 GM129674
6 · The paper itself

Abstract

High rates of glycolysis in tumors have been associated with cancer metastasis, tumor recurrence, and poor outcomes. In this light, single cells that exhibit high glycolysis are specific targets for therapy. However, the study of these cells requires efficient tools for their isolation. We use a droplet microfluidic technique developed in our lab,

Indexed as

Cell SeparationLab-On-A-Chip DevicesSingle-Cell AnalysisCell Line, TumorGlycolysisHumans

Identifiers

PMID32297730
PMCPMC7473507
OpenAlexW3016733706

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.