ArticleCerebral cortex (New York, N.Y. : 1991)2020
Mapping Short Association Fibers in the Early Cortical Visual Processing Stream Using In Vivo Diffusion Tractography.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- White matter variability, cognition, and disorders: a systematic review.Brain structure & function · 2022Pooled it
- Insights into temporal and spatial dynamics of short association fiber formation in the human fetal brain.Science advances · 2026Article
- Congenital blindness reduces myelination in human visual cortex.Science advances · 2026Article
- Quantitative analysis of representation asymmetry in human cadaveric white matter dissection literature.Scientific reports · 2026Article
- Impairment of brain short association fibers across clinical stages in amyotrophic lateral sclerosis: a new biomarker mirroring disease progression.BMC medicine · 2026Article
- Ultra-high gradient connectomics and microstructure MRI scanner for imaging of human brain circuits across scales.Nature biomedical engineering · 2026Article
- Microstructural profiles of the human superficial white matter and their associations to cortical geometry and connectivity.PLoS biology · 2026Article
- Micron-resolution fiber mapping in histology independent of sample preparation.Nature communications · 2025Article
- High-density MRI coil arrays with integrated field monitoring systems for human connectome mapping.Magnetic resonance in medicine · 2025Article
- Micron-resolution fiber mapping in histology independent of sample preparation.bioRxiv : the preprint server for biology · 2025Article
- Short-range human cortico-cortical white matter fibers have thinner axons and are less myelinated compared to long-range fibers despite a similar g-ratio.PLoS biology · 2025Article
- Visualization of functional and effective connectivity underlying auditory descriptive naming.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Romer-EPTI: Rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale diffusion MRI and microstructure imaging.Magnetic resonance in medicine · 2025Article
- Short association fibres form topographic sheets in the human V1-V2 processing stream.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Assessment of the Depiction of Superficial White Matter Using Ultra-High-Resolution Diffusion MRI.Human brain mapping · 2024Article
- Structural and functional connectivity associations with anterior cingulate sulcal variability.Brain structure & function · 2024Article
- Mapping short association fibre connectivity up to V3 in the human brain in vivo.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cortical and white matter substrates supporting visuospatial working memory.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Romer-EPTI: rotating-view motion-robust super-resolution EPTI for SNR-efficient distortion-free in-vivo mesoscale dMRI and microstructure imaging.bioRxiv : the preprint server for biology · 2024Article
- U-fiber diffusion kurtosis and susceptibility characteristics in relapsing-remitting multiple sclerosis may be related to cognitive deficits and neurodegeneration.European radiology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Short association fibers (U-fibers) connect proximal cortical areas and constitute the majority of white matter connections in the human brain. U-fibers play an important role in brain development, function, and pathology but are underrepresented in current descriptions of the human brain connectome, primarily due to methodological challenges in diffusion magnetic resonance imaging (dMRI) of these fibers. High spatial resolution and dedicated fiber and tractography models are required to reliably map the U-fibers. Moreover, limited quantitative knowledge of their geometry and distribution makes validation of U-fiber tractography challenging. Submillimeter resolution diffusion MRI-facilitated by a cutting-edge MRI scanner with 300 mT/m maximum gradient amplitude-was used to map U-fiber connectivity between primary and secondary visual cortical areas (V1 and V2, respectively) in vivo. V1 and V2 retinotopic maps were obtained using functional MRI at 7T. The mapped V1-V2 connectivity was retinotopically organized, demonstrating higher connectivity for retinotopically corresponding areas in V1 and V2 as expected. The results were highly reproducible, as demonstrated by repeated measurements in the same participants and by an independent replication group study. This study demonstrates a robust U-fiber connectivity mapping in vivo and is an important step toward construction of a more complete human brain connectome.
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