Evidence map›Paper›PMID 32297437›Full record

ArticleThe oncologist2020

Opioid Prescribing Trends in Women Following Mastectomy or Breast-Conserving Surgery Before and After the 2014 Federal Reclassification of Hydrocodone.

Derrick C Gibson, Lin-Na Chou, Mukaila A Raji, Jacques G Baillargeon, Yong-Fang Kuo

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The oncologist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Derrick C GibsonDepartment of Preventive Medicine and Population Health, University of Texas Medical Branch - Galveston, Galveston, Texas, USA.ORCID 0000-0001-6355-9432
Lin-Na ChouDepartment of Preventive Medicine and Population Health, University of Texas Medical Branch - Galveston, Galveston, Texas, USA.
Mukaila A RajiDepartment of Internal Medicine, Division of Geriatrics, University of Texas Medical Branch - Galveston, Galveston, Texas, USA.
Jacques G BaillargeonDepartment of Preventive Medicine and Population Health, University of Texas Medical Branch - Galveston, Galveston, Texas, USA.
Yong-Fang KuoDepartment of Preventive Medicine and Population Health, University of Texas Medical Branch - Galveston, Galveston, Texas, USA.
The University of Texas Medical Branch at Galveston · US

Funding

Pattern, Variation and Outcomes of Opioid Prescription in Older AdultsR01DA039192 · NIDA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KUO, YONG-FANG, RAJI, MUKAILA A · 2016 to 2023
$3.1M
UTMB Health Services Research Training ProgramT32HS026133 · AHRQ · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KUO, YONG-FANG · 2018 to 2023
$699k
AHRQ HHS T32 HS026133NIDA NIH HHS R01 DA039192
6 · The paper itself

Abstract

backgroundGiven concerns about suboptimal pain management for actively treated cancer patients following the 2014 federal reclassification of hydrocodone, we examined changes in patterns of opioid prescribing among surgical breast cancer patients. MATERIALS AND

methodsData from a large nationally representative commercial health insurance program from 2009 to 2017 were used to identify women aged 18 years and older who were diagnosed with carcinoma in-situ or malignant breast cancer and received breast-conserving surgery or mastectomy from 2010 to 2016. Generalized linear mixed models were used to estimate the adjusted odds ratio (aOR) for receipt of ≥1-day, >30-day, or ≥ 90-day supply of opioids in the 12 months following surgery adjusting for demographics, cancer treatment-related characteristics, and preoperative opioid use.

resultsA total of 60,080 patients were included in the study. Surgically treated breast cancer patients in 2015 (aOR = 0.90, 0.84-0.97) and 2016 (aOR = 0.80, 0.74-0.86) were less likely to receive ≥1-day supply of opioid prescriptions when compared with patients in 2013. Patients who had surgery in 2015 (aOR = 0.89, 0.81-0.98) and 2016 (aOR = 0.80, 0.73-0.87) were also less likely to receive >30-day supply of prescription opioids in the 12 months following surgery. However, only surgical breast cancer patients in 2016 were less likely to receive ≥90-day supply (aOR = 0.86, 0.76-0.98).

conclusionSurgically treated breast cancer patients are less likely to receive short- and long-term opioid prescriptions following the implementation of hydrocodone rescheduling. Further studies on the potential impact of federal policy on cancer patient pain management are needed. IMPLICATIONS FOR PRACTICE: Clinicians and researchers with diverse perspectives should be included as stakeholders during policy development for restricting opioid prescriptions. Stakeholders can identify potential unintended consequences early and help identify methods to mitigate concerns, specifically as it relates to policy that influences how providers manage pain for actively treated cancer patients. This work shows how federal policy may have led to declines in opioid prescribing for breast cancer patients who underwent mastectomy or breast-conserving surgery.

Indexed as

Analgesics, OpioidBreast NeoplasmsDrug PrescriptionsFemaleHumansHydrocodoneMastectomyMastectomy, SegmentalPractice Patterns, Physicians'Analgesics, OpioidHydrocodoneBreast neoplasmsHydrocodoneMastectomyPolicy

Identifiers

PMID32297437
PMCPMC7160397
OpenAlexW2991788843

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.