Evidence map›Paper›PMID 32297282›Full record

Observational studyAdvances in therapy2020

Management of Patients with Overactive Bladder in Brazil: A Retrospective Observational Study Using Data From the Brazilian Public Health System.

Greta Lozano-Ortega, Daniel B Ng, Shelagh M Szabo, Alison M Deighton, Bruno Riveros, Anne Guttschow, Katherine L Gooch, Cristiano M Gomes

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Age-dependent effects of the βPflugers Archiv : European journal of physiology · 2024
    Article
  2. Current pharmacotherapy of overactive bladder.International braz j urol : official journal of the Brazilian Society of Urology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Greta Lozano-OrtegaBroadstreet Health Economics and Outcomes Research, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0002-5378-0544
Daniel B NgAstellas Pharma Global Development, Inc., Northbrook, IL, USA. daniel.ng@astellas.com.
Shelagh M SzaboBroadstreet Health Economics and Outcomes Research, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0002-9044-3192
Alison M DeightonBroadstreet Health Economics and Outcomes Research, Vancouver, BC, Canada.
Bruno RiverosMAPESolutions, Sao Paulo, Brazil.
Anne GuttschowAstellas Pharma Global Development, Inc., Northbrook, IL, USA.
Katherine L GoochAstellas Pharma Global Development, Inc., Northbrook, IL, USA.
Cristiano M GomesDivision of Urology, Department of Surgery, University of Sao Paulo-Sao Paulo/SP School of Medicine, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0002-8486-4003
Astellas Pharma (United States) · USVancouver Coastal Health · CAUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn Brazil, current data on the use of healthcare resources to manage individuals with overactive bladder (OAB) are lacking. This study aimed to characterize contemporary treatment and the economic burden among patients with OAB managed under the Brazilian public health system (Sistema Único de Saúde [SUS]).

methodsPopulation-based data from January to December of 2015 were acquired from Brazil's public health database. Adults at least 18 years of age with an ICD-10 diagnostic code for OAB within the period were included. Records of outpatient visits, hospitalizations, and onabotulinumtoxinA injections were used to calculate estimates of resource use and costs (in Brazilian reals [R$]) among those with OAB (frequency [%] and mean (standard deviation [SD]) as appropriate). Patient identifiers were not available, so a record linkage methodology was used to match medical encounters to individuals. Pharmacologic management of OAB was informed by government medication purchases available from the official Brazilian government databases.

resultsDuring 2015, 26,640 patients with OAB were identified. All cohort members had at least one outpatient visit and 15,349 (57.6%) were hospitalized. Of the study cohort, 10.0% visited a general practitioner (GP), 41.3% visited a specialist, and 52.0% visited other non-medical healthcare practitioners within the year. Mean (SD) healthcare costs among the study cohort totaled R$355 (R$866) per patient per year; and were R$291 (R$654), R$27 (R$130), R$27 (R$30), and R$11 (R$17) for hospitalizations, GP, specialist, and non-medical healthcare practitioner visits per patient per year, respectively. Regional analysis of reported government medication purchases suggested that access to OAB treatments is highly limited.

conclusionsHigh resource use and costs were estimated among patients with OAB managed within the SUS. These data provide a snapshot of the management of patients with OAB in Brazil, with the patients seeking treatment under SUS likely representing a more burdened subpopulation.

Indexed as

Patient Care ManagementUrinary Bladder, OveractiveBotulinum Toxins, Type ABrazilFemaleHealth Care CostsHospitalizationHumansMaleMiddle AgedNeuromuscular AgentsPublic HealthRetrospective StudiesBotulinum Toxins, Type ANeuromuscular AgentsBrazil public healthcareEconomic burdenOveractive bladderPatient managementUrology

Identifiers

PMID32297282
PMCPMC7467463
OpenAlexW3016888407

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.