SynthesisEuropean geriatric medicine2020
Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient's experience.
Synthesis in European geriatric medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Social isolation and loneliness effects on medication adherence in older adults: perspectives from a systematic review.BMC public health · 2026Pooled it
- COPD-patients' perspective on adherence to therapy and its integration into a systematic literature review.BMC pulmonary medicine · 2026Pooled it
- Impact of COVID-19 Pandemic on Adherence to Chronic Therapies: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- An Adaptable Framework for Factors Contributing to Medication Adherence: Results from a Systematic Review of 102 Conceptual Frameworks.Journal of general internal medicine · 2021Pooled it
- Confronting finitude and treatment adherence in older adults with chronic diseases: a qualitative study.BMC geriatrics · 2026Article
- Patient experience, satisfaction, and adherence: Mediating roles of communication and outcome quality among geriatrics.Narra J · 2026Article
- Lifestyle Behaviours and Antiplatelet Medication Adherence Among Post-Percutaneous Coronary Intervention Patients in Saudi Arabia: Implications for Holistic Cardiovascular Nursing Care.Healthcare (Basel, Switzerland) · 2026Article
- Medication adherence among geriatric patients with chronic diseases in rural China: a social ecological model perspective.BMC geriatrics · 2026Article
- Medication burden, adherence and health-related quality of life in COPD in China: a multilevel health system study.BMJ public health · 2026Article
- Evidence-based nursing to reduce polypharmacy risks in older cholecystectomy patients.World journal of gastrointestinal surgery · 2025Article
- Promoting Medication Adherence in the Elderly: Factors and Insights From a Cross-Sectional Study.Aging medicine (Milton (N.S.W)) · 2025Article
- Depression, anxiety, and medication adherence among Sudanese refugees with chronic illnesses in Aftit refugee camp, northwest Ethiopia: a cross-sectional study.Global health action · 2025Article
- Introducing the Adherence Promotion with Person-centered Technology (APPT) trial: Rationale, methods, and baseline characteristics.Contemporary clinical trials · 2025Article
- Discontinuing Chronic Medications Suggested for Deprescribing in Routine Clinical Practice: Nationwide Evidence From Routinely Collected Data in Swedish Older Adults.Basic & clinical pharmacology & toxicology · 2025Article
- 'You would rather not fill your body with pills'-patient perspectives on polypharmacy and medication reviews by pharmacists in general practice.Scandinavian journal of primary health care · 2025Article
- Relationship Between Depression and Medication Adherence in Older Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis.Health science reports · 2025Review
- Identifying Key Factors Influencing Non-adherence to Imatinib Therapy in Patients With Chronic Myeloid Leukemia.Cureus · 2025Article
- Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life.Medicina (Kaunas, Lithuania) · 2025Review
- Digital interventions addressing the unmet needs of older adults with multimorbidity: a mixed-methods persona design approach.Frontiers in public health · 2025Article
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
purposeMedication non-adherence represents a socially relevant challenge, particularly when interlinked to multiple chronic diseases and polypharmacy. Non-adherence rates affect treatment efficacy and increase health care costs. The aim of the study was to identify factors influencing medication adherence in the older adults through a systematic review of qualitative studies on patients' experience.
methodsTwo electronic databases were searched for qualitative studies on medication adherence in chronic diseases (hypertension, heart disease, COPD, asthma) involving people aged 65 + . The systematic review was performed according to the PRISMA statement guidelines, employing theoretical frameworks of the ABC Taxonomy of patient adherence and Three Factor model of determinants of behaviour.
resultsThe initial database search identified 1234 records, of which 39 studies were considered eligible. Most of the studies focused on hypertension and were conducted in English-speaking countries. According to the ABC Taxonomy, Persistence and Implementation were the most often considered phases. Considering the Three Factor model, the most often reported themes were Information and Strategies upon being adherent. Stemming from the review findings and the patients' narratives, a new integrated model was proposed. It reports the patient's decisional flowchart describing barriers and facilitators (personal, social and environmental) to adherence.
conclusionMedication adherence is a complex and multifaceted process. The implementation of theoretical frameworks along with a patient-centred perspective may provide clinicians with useful suggestions for clinical practice, enhancing the patient's ability to adhere.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.