Evidence map›Paper›PMID 32297180›Full record

ArticleInternational urology and nephrology2020

Predictors of symptom burden among hemodialysis patients: a cross-sectional study at 13 hospitals.

Reema Karasneh, Sayer Al-Azzam, Shoroq M Altawalbeh, Osama Y Alshogran, Sahar Hawamdeh

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reema KarasnehDepartment of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, P.O. Box 566, Irbid, 21163, Jordan. reema.karasneh@yu.edu.jo.ORCID http://orcid.org/0000-0002-2919-1280
Sayer Al-AzzamClinical Pharmacy Department, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Shoroq M AltawalbehClinical Pharmacy Department, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Osama Y AlshogranClinical Pharmacy Department, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Sahar HawamdehClinical Pharmacy Department, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

Funding

Deanship of Scientific Research, Jordan University of Science and Technology (JO) 67/2018
6 · The paper itself

Abstract

purposeThis study investigated the clinical characteristics and symptomatology of ESRD patients in Jordan taking a multidimensional approach.

methodsThis was a cross-sectional study that included a cohort of 620 patients undergoing maintenance hemodialysis (HD). Data were retrieved via patient survey administration and electronic health records. A modified version of the Charlson Comorbidity index (CCI) was utilized to assess comorbidity. Symptoms were assessed using the validated Arabic version of the CKD Symptom Burden Index (CKD-SBI).

resultsThe mean (± SD) age of participants was 50.9 ± 16.1 years, with the 59.8% being males. Diabetes was the leading cause of kidney disease among patients (29.2%), followed by hypertension (20.7%) and medication use (8.6%). Common comorbidities included hypertension (72.4%), diabetes (38.4%), and cardiovascular disease (18.7%). Patients experienced 13 CKD-related symptoms on average, with a total symptom burden score of 29.6. Muscle strain was the most common symptom (62.6%), followed by itchiness (59.7%), nervousness (57.7%), and anxiety (57.7%). Charlson comorbidity index (CCI) [β = 0.88, 95% CI (0.34-1.41)], male gender [β = - 5.59; 95% CI (- 8.34 to - 2.85)], higher educational level [β = - 3.38; 95% CI (- 6.39 to - 0.37)], and number of dialysis sessions/week (β = 6.22, 95% CI 3.37-9.07) were independent predictors of total symptom burden. Similarly, these factors predicted symptom troublesomeness, intensity, and recurrence.

conclusionA holistic clinical picture of ESRD that includes multidimensional symptom assessment is warranted for better disease management and resource allocation. Our paper identifies key characteristic of this population and factors contributing to total symptom burden.

Indexed as

Renal DialysisAdultAgedCost of IllnessCross-Sectional StudiesFemaleHospitalsHumansMaleMiddle AgedRenal Insufficiency, ChronicSymptom AssessmentESRDKidney diseasePredictorsSymptom burden

Identifiers

PMID32297180

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