Evidence map›Paper›PMID 32297164›Full record

ArticleMagma (New York, N.Y.)2020

Quantitative measurement of atheroma burden: reproducibility in serial studies of atherosclerotic femoral arteries.

Yuting Wang, Xinke Liu, Henrik Haraldsson, Chengcheng Zhu, Megan Ballweber, Warren Gasper, Thomas Hatsukami, David Saloner

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yuting Wang *Department of Radiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 2006 Xiyuan Avenue, Chengdu, 611731, China. wangyuting_330@163.com.
Xinke Liu *Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Henrik HaraldssonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Chengcheng ZhuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Megan BallweberDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Warren GasperDivision of Vascular and Endovascular Surgery, University of California, San Francisco, CA, USA.
Thomas HatsukamiDepartment of Surgery, University of Washington, Seattle, WA, USA.
David SalonerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
University of California, San Francisco · USBeijing Institute of Neurosurgery · CNSeattle University · US

Funding

Targeted Endovascular Treatment of Inflammation for Vascular Healing in HumansR01HL128816 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SALONER, DAVID A · 2015 to 2019
$2.7M
NHLBI NIH HHS R01 HL128816NIH HHS R01HL128816-01
6 · The paper itself

Abstract

objectivesThis study aims to evaluate the reproducibility of measures of plaque morphology in serially acquired black-blood MRI of untreated atherosclerotic femoral arteries. MATERIALS AND

methodsMR studies was obtained from 42 timepoints, on 12 patients with known femoral artery atherosclerosis. Images with a 3D isotropic FLASH with DANTE-prepared black blood contrast (DASH) at a 3-T scanner were acquired at baseline, within 1 week, and at 1 month. Six of the patients were scanned additionally at 6 months. Inter-scan and inter-observer variations of arterial area/volume measurements were evaluated.

resultsMeasurement of vessel area, lumen area, wall area and wall volume showed inter-scan intraclass correlation coefficients (ICC) ranging from 0.92 to 0.97 for 3 scans, 0.91-0.97 for 4 scans, and inter-observer ICCs of 0.89-0.96. Among 3 scans, the coefficients of variance (CV) for the vessel area, lumen area, wall area and wall volume were 4.1%, 6.5%, 7.5%, and 4.4%. CVs among 4 scans ranged from 4.4% to 7.9%, and interobserver CVs ranged from 6.1% to 11.8% for the different area/volume measurements.

conclusionDASH MRI is useful for quantifying atherosclerotic vessel area and volume of femoral arteries with low variability among serial repeated scans and between observers.

Indexed as

AtherosclerosisPlaque, AtheroscleroticCarotid ArteriesFemoral ArteryHumansImaging, Three-DimensionalObserver VariationReproducibility of ResultsAtherosclerosisBlack bloodFemoralMRReproducibility

Identifiers

PMID32297164
PMCPMC8527847
OpenAlexW3017276519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.