Evidence map›Paper›PMID 32297159›Full record

ArticleInternational journal of hematology2020

Effects of stem cell transplantation in patients with peripheral T-cell lymphoma not otherwise specified and angioimmunoblastic T-cell lymphoma.

Satoshi Yamasaki, Shuro Yoshida, Koji Kato, Ilseung Choi, Yutaka Imamura, Kentaro Kohno, Hideho Henzan, Kazuki Tanimoto, Ryosuke Ogawa, Youko Suehiro and 6 more

Abstract read
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In one paragraph

Article in International journal of hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Satoshi YamasakiDepartment of Hematology and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-Ku, Fukuoka, 810-8563, Japan. yamas009@gmail.com.
Shuro YoshidaDepartment of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
Koji KatoMedicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Ilseung ChoiDepartment of Hematology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Yutaka ImamuraDepartment of Hematology, St. Maria Hospital, Kurume, Japan.
Kentaro KohnoDepartment of Medicine, Japan Community Healthcare Organization Kyushu Hospital, Kitakyushu, Japan.
Hideho HenzanDepartment of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
Kazuki TanimotoDepartment of Hematology, Fukuoka Red Cross Hospital, Fukuoka, Japan.
Ryosuke OgawaDepartment of Medicine, Japan Community Healthcare Organization Kyushu Hospital, Kitakyushu, Japan.
Youko SuehiroDepartment of Hematology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Toshihiro MiyamotoMedicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tetsuya EtoDepartment of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
Koichi OhshimaDepartment of Pathology, Kurume University, Kurume, Japan.
Koichi AkashiMedicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Hiromi IwasakiDepartment of Hematology and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-Ku, Fukuoka, 810-8563, Japan.
Fukuoka Blood and Marrow Transplantation Group
Kyushu University · JPNational Kyushu Medical Center · JPHamanomachi Hospital · JPKurume University · JPNational Hospital Organization Kyushu Cancer Center · JPJapanese Red Cross Fukuoka Hospital · JPKyushu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of stem cell transplantation (SCT) in patients with peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) and angioimmunoblastic T-cell lymphoma (AITL) remain controversial. We analyzed the feasibility of SCT and risk factors associated with outcomes of PTCL-NOS and AITL patients to identify the potential clinical efficacy of SCT. We retrospectively analyzed the data of PTCL-NOS (n = 83) and AITL (n = 112) patients who received autologous (n = 10 and 16, respectively) or allogeneic (n = 12 and 4, respectively) SCT, or no SCT (n = 61 and 92, respectively) between 2008 and 2018. All PTCL-NOS and AITL diagnoses were reconfirmed by an experienced hematopathologist. Median age at PTCL-NOS and AITL diagnoses in the SCT group was younger than that in the no SCT group. Significant risk factors for lower overall survival were intermediate-high and high-risk international prognostic indexes in PTCL-NOS patients (P = 0.0052), and a > 2 modified prognostic index for T-cell lymphoma (P = 0.0079) and no SCT (P = 0.028) in AITL patients. Autologous or allogeneic SCT compared with no SCT in AITL patients resulted in 3-year overall survival of 68.6% and 100% vs. 57.2% (P = 0.018). Strategies should be developed to improve selection of PTCL-NOS and AITL patients suitable for SCT and/or additional novel therapies.

Indexed as

Stem Cell TransplantationAdultAgedAged, 80 and overFeasibility StudiesFemaleHumansImmunoblastic LymphadenopathyLymphoma, T-CellLymphoma, T-Cell, PeripheralMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsTransplantation, HomologousAllogeneic stem cell transplantationAngioimmunoblastic T-cell lymphomaAutologous stem cell transplantationPeripheral T-cell lymphoma not otherwise specified

Identifiers

PMID32297159
OpenAlexW3016454850

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.