ArticleEnvironmental science and pollution research international2020
Protective effect assessment of Moringa oleifera against cadmium-induced toxicity in HCT116 and HEK293 cell lines.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- Evaluation of the Potential Cytoprotective Effect of Melatonin in Comparison with Vitamin E and Trolox against CdInternational journal of molecular sciences · 2024Article
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- Cytotoxic evaluation and chemical investigation of tomatoes from plants (Solanum lycopersicum L.) grown in uncontaminated and experimentally contaminated soils.Scientific reports · 2022Article
- Nutritional Value ofNutrients · 2021Article
- Accelerated Solvent Extractions (ASE) ofMolecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cadmium (Cd) is considered one of the widespread toxic metals in the aquatic and terrestrial environments, which is due to its long half-life, non-degradable characteristic, and toxicity. Aqueous extract of freeze-dried Moringa oleifera (Moringaceae family) leaves was examined for protective effect and antioxidant power against Cd toxicity. The results revealed that Moringa aqueous extract (MAE) has contents of total polyphenols and flavonoids about 30.14 mg GAE/g and 18.35 mg QE/g respectively. Furthermore, phenolic compounds in leaves of Moringa were studied using a high-performance liquid chromatography coupled with mass spectrometry (HPLC-MS). Results showed that the largest number of phenolic compounds determined in leaves of Moringa belongs to flavonoids. Moreover, biological properties were determined by radical scavenging capacity (DPPH) and ferric-reducing power (FRAP). Cytoprotective effect and antioxidant power of Moringa extract were assessed using the mitochondrial activity testing method (MTT test), malondialdehyde (MDA), and reactive oxygen species (ROS) production. Results indicate that Moringa aqueous extract have a significant (i) proliferative, (ii) antioxidant, and (iii) cytoprotective effect on HCT116 and HEK293 cells against metal toxicity.
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Registered trials
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