Evidence map›Paper›PMID 32297007›Full record

ReviewCurrent oncology reports2020

Developing Real-world Evidence-Ready Datasets: Time for Clinician Engagement.

James M Snyder, Jacob A Pawloski, Laila M Poisson

Abstract readReview
In one paragraph

Review in Current oncology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James M SnyderDepartment of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI, 48202, USA. jsnyder5@hfhs.org.
Jacob A PawloskiDepartment of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI, 48202, USA.
Laila M PoissonDepartment of Public Health Sciences, Hermelin Brain Tumor Center, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI, 48202, USA.

Funding

Molecular and clinical evaluation of the glioma patient experience to anticipate modern outcomes and guide patient careR01CA222146 · NCI · HENRY FORD HEALTH SYSTEM · PI POISSON, LAILA M · 2018 to 2023
$2.8M
NCI NIH HHS R01 CA222146
6 · The paper itself

Abstract

purpose of reviewReal-world data (RWD) applications in healthcare that support learning health systems and pragmatic clinical trials are gaining momentum, largely due to legislation supporting real-world evidence (RWE) for drug approvals. Clinical notes are thought to be the cornerstone of RWD applications, particularly for conditions with limited effective treatments, extrapolation of treatments from other conditions, or heterogenous disease biology and clinical phenotypes. RECENT

findingsHere, we discuss current issues in applying RWD captured at the point-of-care and provide a framework for clinicians to engage in RWD collection. To achieve clinically meaningful results, RWD must be reliably captured using consistent terminology in the description of our patients. RWD complements traditional clinical trials and research by informing the generalizability of results, generating new hypotheses, and creating a large data network for scientific discovery. Effective clinician engagement in the development of RWD applications is necessary for continued progress in the field.

Indexed as

Datasets as TopicDrug ApprovalElectronic Health RecordsPoint-of-Care SystemsClinical Trials as TopicHumansMolecular BiologyBig dataBioinformatics real-world dataCDECommon data elementsElectronic health recordLearning health systemsNeuroinformaticsNeuro-oncologyPoint-of-carePragmatic clinical trialsPrecision medicineReal-world evidenceRWDRWE

Identifiers

PMID32297007
PMCPMC8214868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.