ArticleNeuroradiology2020
Volumetric and functional connectivity alterations in patients with chronic cervical spondylotic pain.
Article in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Connectomic Mapping of Chronic Musculoskeletal Pain: Neural Circuitries Identified Through a Systematic Review and ALE Meta-Analysis.Neural plasticity · 2026Pooled it
- Abnormalities of brain structure and function in cervical spondylosis: a multi-modal voxel-based meta-analysis.Frontiers in neuroscience · 2024Pooled it
- Brain MRI changes in degenerative cervical myelopathy: a systematic review.EBioMedicine · 2024Pooled it
- Investigation of cerebellar structure and static and dynamic functional connectivity in cervical spondylotic myelopathy patients.Neuroradiology · 2026Article
- Resting-state fMRI reveals brain functional alterations linked to balance disorders in vestibular migraine patients.Scientific reports · 2025Article
- Prevalence and Risk Factors for Cervical Adjacent Segment Disease and Analysis of the Clinical Effect of Revision Surgery: A Minimum of 5 Years' Follow-Up.Global spine journal · 2025Article
- Changes in cerebral cortex activation during upright standing tasks in individuals with chronic neck pain: an fNIRS study.Frontiers in neurology · 2025Article
- Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging.Frontiers in neuroscience · 2025Article
- Sex-specific alterations in functional connectivity and network topology in patients with degenerative cervical myelopathy.Scientific reports · 2024Article
- Abnormal Functional Connectivity Intra- and Inter-Network in Resting-State Brain Networks of Patients with Toothache.Journal of pain research · 2024Article
- Changes of regional brain activity following Tuina therapy for patients with painful cervical spondylosis: a resting-state fMRI study.Frontiers in neurology · 2024Article
- Local abnormal white matter microstructure in the spinothalamic tract in people with chronic neck and shoulder pain.Frontiers in neuroscience · 2024Article
- Greater functional connectivity between the ventral frontal cortex and occipital cortex in herpes zoster patients than post-herpetic neuralgia patients.The British journal of radiology · 2023Article
- Two sides of the same coin: distinct neuroanatomical patterns predict crystallized and fluid intelligence in adults.Frontiers in neuroscience · 2023Article
- From Low-Grade Inflammation in Osteoarthritis to Neuropsychiatric Sequelae: A Narrative Review.International journal of molecular sciences · 2022Review
- Shape deformations of the basal ganglia in patients with classical trigeminal neuralgia: a cross-sectional evaluation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Middle cingulate cortex function contributes to response to non-steroidal anti-inflammatory drug in cervical spondylosis patients: a preliminary resting-state fMRI study.Neuroradiology · 2022Article
- The functional connectivity of the basal ganglia subregions changed in mid-aged and young males with chronic prostatitis/chronic pelvic pain syndrome.Frontiers in human neuroscience · 2022Article
- Image Features of Resting-State Functional Magnetic Resonance Imaging in Evaluating Poor Emotion and Sleep Quality in Patients with Chronic Pain under Artificial Intelligence Algorithm.Contrast media & molecular imaging · 2022Article
- Sex-Dependent Cortical Volume Changes in Patients with Degenerative Cervical Myelopathy.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo explore the structural and functional alterations of the whole brain in patients with chronic cervical spondylotic pain (cCSP).
methodsThe whole-brain three-dimensional (3D) T1 and resting-state functional magnetic resonance imaging (rs-fMRI) data were acquired in 31 patients with cCSP and 30 age- and sex-matched healthy controls. 3D T1 and rs-fMRI data were processed using statistical parametric mapping (SPM) and data processing and analysis of brain imaging (DPABI) toolbox. The parametric differences of voxel-based morphometry (VBM) and resting-state functional connectivity (rs-FC) were calculated between groups, then these measures were correlated with the score of visual analogue scale (VAS) and other clinical indices in patients with cCSP.
resultsPatients with cCSP exhibited reduced gray matter volume (GMV) in the right middle cingulate cortex (MCC), right superior temporal gyrus (STG) and right precuneus compared to healthy controls. Furthermore, patients with cCSP displayed decreased functional connectivity between the right precuneus and bilateral medial prefrontal cortex (mPFC). Additionally, GMV of the right MCC, right STG, and right precuneus, together with rs-FC of the right precuneus to bilateral mPFC, were negatively correlated with the VAS respectively.
conclusionsOur study revealed cerebral morphological and functional abnormalities during the pain process in patients with cCSP, which may provide alternative information for the treatment of cCSP.
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