Evidence map›Paper›PMID 32296723›Full record

ArticleComputing in cardiology2018

A Multi-Scale Investigation of Global Electrical Heterogeneity: Effects of Body Habitus, Respiration, and Tissue Conductivity.

Erick A Perez-Alday, Haibo Ni, Christopher Hamilton, Annabel Li-Pershing, Bernard Jaar, Jose M Monroy-Trujillo, Michelle Estrella, Rulan Parekh, Henggui Zhang, Larisa Tereshchenko

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computing in cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Erick A Perez-AldayOregon Health & Science University, Portland, OR, USA.
Haibo NiUniversity of California Davis, Davis, CA, USA.
Christopher HamiltonOregon Health & Science University, Portland, OR, USA.
Annabel Li-PershingOregon Health & Science University, Portland, OR, USA.
Bernard JaarJohns Hopkins University, Baltimore, MD, USA.
Jose M Monroy-TrujilloJohns Hopkins University, Baltimore, MD, USA.
Michelle EstrellaJohns Hopkins University, Baltimore, MD, USA.
Rulan ParekhJohns Hopkins University, Baltimore, MD, USA.
Henggui ZhangUniversity of Manchester, Manchester, United Kingdom.
Larisa TereshchenkoOregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · USUniversity of California, San Francisco · USJohns Hopkins University · USUniversity of California, Davis · USUniversity of Manchester · GB

Funding

Novel ECG Measures and Risk of Sudden Cardiac DeathR01HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2013 to 2016
$1.5M
Novel ECG measures and risk of sudden cardiac deathR56HL118277 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TERESHCHENKO, LARISA GENNADIEVNA · 2018 to 2018
$396k
NHLBI NIH HHS R01 HL118277NHLBI NIH HHS R56 HL118277
6 · The paper itself

Abstract

Extracardiac factors such as respiration, fluid overload and body habitus have important effects on the ECG voltage. Vectorcardiographic (VCG) Global Electrical Heterogeneity (GEH) is associated with sudden cardiac death (SCD). Risk of SCD is especially high in end-stage renal disease patients (ESRD) on dialysis. However, extracardiac factors challenge ECG interpretation in ESRD patients. The effects of extracardiac factors on GEH have not been fully studied. To1 assess effects of extracardiac factors on ECG, we conducted a multi-scale study. An experimental data of ESRD patients and a previously developed biophysically detailed heart-torso model were used to investigate the effects of respiration, fluid overload and body habitus on the VCG and GEH.

Identifiers

PMID32296723
PMCPMC7158893
OpenAlexW2912253765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.