Evidence map›Paper›PMID 32296691›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Multifunctional Copper-Containing Mesoporous Glass Nanoparticles as Antibacterial and Proangiogenic Agents for Chronic Wounds.

Thomas E Paterson, Alessandra Bari, Anthony J Bullock, Robert Turner, Giorgia Montalbano, Sonia Fiorilli, Chiara Vitale-Brovarone, Sheila MacNeil, Joanna Shepherd

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

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  12. In Vitro Models of Biological Barriers for Nanomedical Research.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Bioactive Materials Promote Wound Healing through Modulation of Cell Behaviors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  15. Article
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  19. Emerging Trends in Nanomaterials for Antibacterial Applications.International journal of nanomedicine · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Thomas E PatersonSchool of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
Alessandra BariDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Anthony J BullockDepartment of Materials Science and Engineering, University of Sheffield, Sheffield, United Kingdom.
Robert TurnerSchool of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
Giorgia MontalbanoDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Sonia FiorilliDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Chiara Vitale-BrovaroneDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Sheila MacNeilDepartment of Materials Science and Engineering, University of Sheffield, Sheffield, United Kingdom.
Joanna ShepherdSchool of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
University of Sheffield · GBPolytechnic University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physiological wound healing process involves a cascade of events which could be affected by several factors resulting in chronic, non-healing wounds. The latter represent a great burden especially when bacterial biofilms are formed. The rise in antibiotic resistance amongst infectious microorganisms leads to the need of novel approaches to treat this clinical issue. In this context, the use of advanced biomaterials, which can enhance the physiological expression and secretion of the growth factors involved in the wound healing process, is gaining increasing attention as a robust and appealing alternative approach. Among them, mesoporous glasses are of particular interest due to their excellent textural properties and to the possibility of incorporating and releasing specific therapeutic species, such as metallic ions. One of the most attractive therapeutic ions is copper thanks to its proangiogenic and antibacterial effects. In this contribution, copper containing mesoporous glass nanoparticles were proposed as a multifunctional device to treat chronic wounds. The developed nanoparticles evidenced a very high specific surface area (740 m

Indexed as

antibacterialbiomaterialschronic wound and burn healingglass nanoparticlesmesoporousmultifunctionalityproangiogenic

Identifiers

PMID32296691
PMCPMC7136418
OpenAlexW3014339584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.