Evidence map›Paper›PMID 32296588›Full record

ArticleCancer biology & medicine2020

Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma.

Olivia Leblanc, Sophie Vacher, Charlotte Lecerf, Emmanuelle Jeannot, Jerzy Klijanienko, Frédérique Berger, Caroline Hoffmann, Valentin Calugaru, Nathalie Badois, Anne Chilles and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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  7. Dual inhibition of HERs and PD-1 counteract resistance in KRASJournal of experimental & clinical cancer research : CR · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Olivia LeblancDepartment of Genetics, Curie Institute, PSL Research University, Paris 75005, France.
Sophie VacherDepartment of Genetics, Curie Institute, PSL Research University, Paris 75005, France.
Charlotte LecerfDepartment of Drug Development and Innovation (D3i), Curie Institute, PSL Research University, Paris 75005, France.
Emmanuelle JeannotDepartment of Genetics, Curie Institute, PSL Research University, Paris 75005, France.
Jerzy KlijanienkoDepartment of Pathology, Curie Institute, PSL Research University, Paris 75005, France.
Frédérique BergerDepartment of Biostatistics, Curie Institute, PSL Research University, Paris 75005, France.
Caroline HoffmannDepartment of Surgery, Curie Institute, PSL Research University, Paris 75005, France.
Valentin CalugaruDepartment of Radiotherapy, Curie Institute, PSL Research University, Paris 75005, France.
Nathalie BadoisDepartment of Surgery, Curie Institute, PSL Research University, Paris 75005, France.
Anne ChillesDepartment of Radiotherapy, Curie Institute, PSL Research University, Paris 75005, France.
Maria LesnikDepartment of Surgery, Curie Institute, PSL Research University, Paris 75005, France.
Samar KrhiliDepartment of Surgery, Curie Institute, PSL Research University, Paris 75005, France.
Ivan BiecheDepartment of Genetics, Curie Institute, PSL Research University, Paris 75005, France.
Christophe Le TourneauDepartment of Drug Development and Innovation (D3i), Curie Institute, PSL Research University, Paris 75005, France.
Maud KamalDepartment of Drug Development and Innovation (D3i), Curie Institute, PSL Research University, Paris 75005, France.ORCID 0000-0003-1466-0950
Université Paris Sciences et Lettres · FRInserm · FRInstitut Curie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorCetuximabClass I Phosphatidylinositol 3-KinasesDNA Mutational AnalysisDrug Resistance, NeoplasmErbB ReceptorsFemaleFollow-Up StudiesGain of Function MutationHead and Neck NeoplasmsHumansImmunohistochemistryMaleMiddle AgedProgression-Free SurvivalProto-Oncogene Proteins p21(ras)Biomarkers, TumorCetuximabClass I Phosphatidylinositol 3-KinasesEGFR protein, humanErbB ReceptorsHRAS protein, humanKRAS protein, humanPIK3CA protein, humanProto-Oncogene Proteins p21(ras)biomarkercetuximabHead and neck squamous cell carcinomaPIK3CARAS

Identifiers

PMID32296588
PMCPMC7142836
OpenAlexW3019785843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.