Evidence map›Paper›PMID 32296538›Full record

ArticleRegenerative biomaterials2020

Preparation and characterization of methacrylated gelatin/bacterial cellulose composite hydrogels for cartilage tissue engineering.

Liling Gu, Tao Li, Xiongbo Song, Xianteng Yang, Senlei Li, Long Chen, Pingju Liu, Xiaoyuan Gong, Cheng Chen, Li Sun

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 115 citations in OpenAlex.

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  8. Production of Bacterial Exopolysaccharides: Xanthan and Bacterial Cellulose.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Liling GuMedical College, Guizhou University, Guiyang 550025, China.
Tao LiCenter for Joint Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Xiongbo SongCenter for Joint Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Xianteng YangDepartment of Orthopedics, Guizhou Provincial People's Hospital, Guiyang 550002, China.
Senlei LiDepartment of Orthopedics, Guizhou Provincial People's Hospital, Guiyang 550002, China.
Long ChenDepartment of Orthopedics, Guizhou Provincial People's Hospital, Guiyang 550002, China.
Pingju LiuZunyi Traditional Chinese Medicine Hospital, Zunyi 563099, China.
Xiaoyuan GongCenter for Joint Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Cheng ChenCenter for Joint Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.ORCID 0000-0002-7323-1104
Li SunDepartment of Orthopedics, Guizhou Provincial People's Hospital, Guiyang 550002, China.
Army Medical University · CNGuizhou Provincial People's Hospital · CNFirst People’s Hospital of Zunyi · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methacrylated gelatin (GelMA)/bacterial cellulose (BC) composite hydrogels have been successfully prepared by immersing BC particles in GelMA solution followed by photo-crosslinking. The morphology of GelMA/BC hydrogel was examined by scanning electron microscopy and compared with pure GelMA. The hydrogels had very well interconnected porous network structure, and the pore size decreased from 200 to 10 µm with the increase of BC content. The composite hydrogels were also characterized by swelling experiment, X-ray diffraction, thermogravimetric analysis, rheology experiment and compressive test. The composite hydrogels showed significantly improved mechanical properties compared with pure GelMA. In addition, the biocompatility of composite hydrogels were preliminarily evaluated using human articular chondrocytes. The cells encapsulated within the composite hydrogels for 7 days proliferated and maintained the chondrocytic phenotype. Thus, the GelMA/BC composite hydrogels might be useful for cartilage tissue engineering.

Indexed as

bacterial cellulosecartilage tissue engineeringhydrogelmethacrylated gelatin

Identifiers

PMID32296538
PMCPMC7147361
OpenAlexW3035659597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.