Evidence map›Paper›PMID 32296525›Full record

ArticleClinical kidney journal2020

Impact of age on cardiovascular drug use in patients with chronic kidney disease.

Cédric Villain, Sophie Liabeuf, Marie Metzger, Christian Combe, Denis Fouque, Luc Frimat, Christian Jacquelinet, Maurice Laville, Serge Briançon, Ronald L Pisoni and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03381950 (Chronic Kidney Disease - Renal Epidemiology and Information Network), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03381950 completednot on this map

Chronic Kidney Disease - Renal Epidemiology and Information Network: The CKD-REIN Cohort

TypeobservationalSponsorInstitut National de la Santé Et de la Recherche Médicale, FranceRan2013 to 2020Enrolled3,033ConditionsRenal Insufficiency, Chronic
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Associations with age and glomerular filtration rate in a referred population with chronic kidney disease: methods and baseline data from a UK multicentre cohort study (NURTuRE-CKD).Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  5. Ageing meets kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  6. Ageing meets kidney disease.Clinical kidney journal · 2022
    Article
  7. Article
  8. The need for a cardionephrology subspecialty.Clinical kidney journal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Cédric VillainService de Néphrologie-Dialyse, CHU Ambroise Paré, APHP, Boulogne-Billancourt, France.
Sophie LiabeufCESP, INSERM Unité 1018, Equipe 5 EpRec, Université Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif, France.
Marie MetzgerCESP, INSERM Unité 1018, Equipe 5 EpRec, Université Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif, France.
Christian CombeService de Néphrologie Transplantation Dialyse Aphérèses, CHU de Bordeaux, Bordeaux, France.
Denis FouqueUniversité de Lyon, Service de Néphrologie, CarMeN INSERM 1060, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France.
Luc FrimatCHRU Nancy-Brabois, Vandœuvre-lès-Nancy, France.
Christian JacquelinetCESP, INSERM Unité 1018, Equipe 5 EpRec, Université Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif, France.
Maurice LavilleUniversité de Lyon, Service de Néphrologie, CarMeN INSERM 1060, Centre Hospitalier Lyon-Sud, Pierre-Bénite, France.
Serge BriançonINSERM CIC-EC CIE6 - EA 4360 Apemac, Nancy Université, Vandœuvre-lès-Nancy, France.
Ronald L PisoniArbor Research Collaborative for Health, Ann Arbor, MI, USA.
Nicolas MansencalCESP, INSERM Unité 1018, Equipe 5 EpRec, Université Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif, France.
Bénédicte StengelCESP, INSERM Unité 1018, Equipe 5 EpRec, Université Paris-Sud, UVSQ, Université Paris-Saclay, Villejuif, France.
Ziad A MassyService de Néphrologie-Dialyse, CHU Ambroise Paré, APHP, Boulogne-Billancourt, France.
Université Paris-Sud · FRInserm · FRUniversité Claude Bernard Lyon 1 · FRArbor Research Collaborative for Health · USUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly patients with chronic kidney disease (CKD) are often excluded from clinical trials; this may affect their use of essential drugs for cardiovascular complications. We sought to assess the impact of age on cardiovascular drug use in elderly patients with CKD.

methodsWe used baseline data from the Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort including 3033 adult patients with CKD Stages 3 and 4. We studied the use of recommended drugs for coronary artery disease (CAD), stroke and atrial fibrillation by age, after adjusting for socio-demographic and clinical conditions.

resultsThe patients' mean age was 66.8 years (mean estimated glomerular filtration rate 32.9 mL/min/1.73 m

conclusionsIn patients with CKD, older age

Indexed as

atrial fibrillationchronic kidney diseasecoronary artery diseaseelderlystrokeunderuse

Identifiers

PMID32296525
PMCPMC7147308
OpenAlexW2950519729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.