Evidence map›Paper›PMID 32296440›Full record

ArticleFrontiers in immunology2020

Molecular and Cellular Interactions of Scavenger Receptor SR-F1 With Complement C1q Provide Insights Into Its Role in the Clearance of Apoptotic Cells.

Catherine Wicker-Planquart, Samy Dufour, Pascale Tacnet-Delorme, Isabelle Bally, Yves Delneste, Philippe Frachet, Dominique Housset, Nicole M Thielens

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. CanPharmaceuticals (Basel, Switzerland) · 2025
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  9. The role of secreted proteins in efferocytosis.Frontiers in cell and developmental biology · 2023
    Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Catherine Wicker-PlanquartUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Samy DufourUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Pascale Tacnet-DelormeUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Isabelle BallyUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Yves DelnesteCRCINA, INSERM, Université de Nantes, Université d'Angers, Angers, France.
Philippe FrachetUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Dominique HoussetUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Nicole M ThielensUniversité Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Institut de Biologie Structurale · FRCEA Grenoble · FRCentre National de la Recherche Scientifique · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInserm · FRUniversité Grenoble Alpes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The scavenger receptor SR-F1 binds to and mediates the internalization of a wide range of ligands, and is involved in several immunological processes. We produced recombinant SR-F1 ectodomain and fragments deleted from the last 2 or 5 C-terminal epidermal growth factor-like modules and investigated their role in the binding of acetylated low density lipoprotein (AcLDL), complement C1q, and calreticulin (CRT). C1q measured affinity was in the 100 nM range and C1q interaction occurs

Indexed as

ApoptosisCalreticulinCell CommunicationComplement C1qHumansMacrophagesPhagocytosisScavenger Receptors, Class FTHP-1 CellsCalreticulinCALR protein, humanComplement C1qSCARF1 protein, humanScavenger Receptors, Class Fapoptosiscomplement C1qinteractionphagocytosisscavenger receptor SR-F1SPR

Identifiers

PMID32296440
PMCPMC7137648
OpenAlexW3014235891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.