Evidence map›Paper›PMID 32296350›Full record

ArticleFrontiers in psychiatry2020

Urinary Amine and Organic Acid Metabolites Evaluated as Markers for Childhood Aggression: The ACTION Biomarker Study.

Fiona A Hagenbeek, Peter J Roetman, René Pool, Cornelis Kluft, Amy C Harms, Jenny van Dongen, Olivier F Colins, Simone Talens, Catharina E M van Beijsterveldt, Marjolein M L J Z Vandenbosch and 10 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Effect ofFrontiers in microbiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Fiona A HagenbeekDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Peter J RoetmanCurium-LUMC, Department of Child and Adolescent Psychiatry, Leiden University Medical Center, Leiden, Netherlands.
René PoolDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Cornelis KluftGood Biomarker Sciences, Leiden, Netherlands.
Amy C HarmsDivision of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden University, Leiden, Netherlands.
Jenny van DongenDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Olivier F ColinsCurium-LUMC, Department of Child and Adolescent Psychiatry, Leiden University Medical Center, Leiden, Netherlands.
Simone TalensGood Biomarker Sciences, Leiden, Netherlands.
Catharina E M van BeijsterveldtDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Marjolein M L J Z VandenboschDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Eveline L de ZeeuwDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Sébastien DéjeanToulouse Mathematics Institute, University of Toulouse, CNRS, Toulouse, France.
Vassilios FanosDepartment of Surgical Sciences, University of Cagliari and Neonatal Intensive Care Unit, Cagliari, Italy.
Erik A EhliAvera Institute for Human Genetics, Sioux Falls, SD, United States.
Gareth E DaviesAvera Institute for Human Genetics, Sioux Falls, SD, United States.
Jouke Jan HottengaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Thomas HankemeierDivision of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden University, Leiden, Netherlands.
Meike BartelsDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Robert R J M VermeirenCurium-LUMC, Department of Child and Adolescent Psychiatry, Leiden University Medical Center, Leiden, Netherlands.
Dorret I BoomsmaDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

Funding

EPA EP-C-15-001
6 · The paper itself

Abstract

Biomarkers are of interest as potential diagnostic and predictive instruments in personalized medicine. We present the first urinary metabolomics biomarker study of childhood aggression. We aim to examine the association of urinary metabolites and neurotransmitter ratios involved in key metabolic and neurotransmitter pathways in a large cohort of twins (

Indexed as

aminesbiomarkerschildhood aggressionmetabolitesmetabolomicsneurotransmittersorganic acidsoxidative stress

Identifiers

PMID32296350
PMCPMC7138132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.